Preparation of Phospholipid Vesicle-Templated Calcium Phosphate Nanostructures and Their Cytocompatibility
Preparation of Phospholipid Vesicle-Templated Calcium Phosphate Nanostructures and Their Cytocompatibility
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DOI：
10.1021/acs.cgd.6b00469
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发表时间：
2016-04
影响因子：
3.8
通讯作者：
M. Tagaya;Tadashi Yamaguchi;Kota Shiba
中科院分区：
文献类型：
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作者：
M. Tagaya;Tadashi Yamaguchi;Kota Shiba
利用磷脂囊泡（PV）模板在模拟体液中研究了磷酸钙（CP）纳米结构的形成。成功制备了PV/water核心（直径：194 nm）周围的CP纳米壳，显示了混合纳米结构。冻干后的纳米杂化膜在纳米尺度上表现出CP/PV排列和成骨细胞样细胞的粘附/增殖，表明纳米杂化结构具有细胞相容性。
Calcium phosphate (CP) nanostructure formation using a phospholipid vesicle (PV) template was investigated in a simulated body fluid. The CP nanoshells surrounding a PV/water core (diameter: 194 nm) were successfully prepared to show the hybrid nanostructures. The lyophilized cast films of the nanohybrids exhibited the CP/PV arrangements at nanometer scales as well as osteoblast-like cell adhesion/proliferation, suggesting cytocompatible nanohybrid structures.