Measuring the Hydrodynamic Size of Nanoparticles in Aqueous Media Using Batch-Mode Dynamic Light Scattering

Measuring the Hydrodynamic Size of Nanoparticles in Aqueous Media Using Batch-Mode Dynamic Light Scattering
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DOI:
10.1007/978-1-60327-198-1_4
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发表时间:
2011-01-01
期刊:
CHARACTERIZATION OF NANOPARTICLES INTENDED FOR DRUG DELIVERY
影响因子:
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通讯作者:
Clogston, Jeffrey D.
Clogston, Jeffrey D.
中科院分区:
其他
文献类型:
--
作者:
Hackley, Vincent A.;Clogston, Jeffrey D.

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Particle size characterization is of particular importance to nanomedicine. The size similarity of nanoparticles to biological moieties is believed to impart many of their unique medical properties. Here we present a method for sample preparation and the determination of mean nanoparticle size (hydrodynamic diameter) using batch-mode dynamic light scattering (DLS) in dilute aqueous suspensions. We then demonstrate this method for 30 nm colloidal gold.