Design and Synthesis of Helically Chiral Spirocyclic P3 Phosphazenes and Characterization of Their Onium Salts
Design and Synthesis of Helically Chiral Spirocyclic P3 Phosphazenes and Characterization of Their Onium Salts
复制标题
螺旋手性螺环P3磷腈的设计与合成及其鎓盐的表征
作者：
M. Terada;K. Goto;M. Oishi;T. Takeda;E. Kwon;A. Kondoh
螺旋手性螺环P3磷腈是一类新型的手性有机超强碱。新设计的手性P3磷腈是从市售来源经过几个步骤合成的，并通过对其鎓盐的X射线晶体学分析进行表征。用制备型手性固定相HPLC法得到了光学纯的P3磷腈盐，并确定了其螺旋手性的绝对构型。
Helically chiral spirocyclic P3 phosphazenes were designed as a novel family of chiral organosuperbases. The newly designed chiral P3 phosphazenes were synthesized from commercially available sources in several steps and characterized by X-ray crystallographic analysis of their onium salts. The optically pure P3 phosphazenium salt was obtained by using preparative chiral stationary phase HPLC and the absolute configuration of the helical chirality was determined.