Does serum ferritin correlate with coronary angiography findings?
Does serum ferritin correlate with coronary angiography findings?
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DOI：
10.1016/s0167-5273(99)00020-0
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发表时间：
1999-05-15
影响因子：
3.5
通讯作者：
Brizolara, ML
中科院分区：
文献类型：
--
作者：
Manfroi, WC;Zago, AJ;Brizolara, ML
背景：许多流行病学研究表明血清铁蛋白水平与冠心病之间存在正相关关系。在这项前瞻性研究中，我们评估了血清铁蛋白水平与冠状动脉粥样硬化程度之间的关系。方法：我们研究了307名连续接受冠状动脉造影术的患者(男性占60.9%，年龄60.1+/-11.0岁)。记录所有患者的冠状动脉疾病危险因素、血脂和铁蛋白水平以及临床特征。两位因临床和实验室数据而失明的有经验的心脏病专家回顾了这些电影。血管造影术中显著的冠状动脉疾病(CAD)被定义为直径大于50%的狭窄。结果：在307例患者中，196例(63.8%)的冠状动脉造影显示有明显的冠心病。显著冠心病的发生与铁蛋白水平(P=0.015)和患者年龄(P
Background: A number of epidemiological studies have described a positive relationship between serum ferritin levels and coronary heart disease. In this prospective study, we evaluated the association between serum ferritin levels and the angiographic extent of coronary atherosclerosis. Method: We studied 307 consecutive patients (60.9% male, age 60.1+/-11.0 years) referred for diagnostic coronary angiography. Risk factors for coronary artery disease, lipids and ferritin levels, as well clinical characteristics were recorded from all patients. Two experienced cardiologists blinded for clinical and laboratory data reviewed the cinefilms. Angiographic significant coronary artery disease (CAD) was defined as any more than a 50% diameter stenosis. Results: From the 307 patients, 196 (63.8%) were found to have angiographic significant CAD. The presence of significant CAD was associated with ferritin levels (P=0.015) as well as patient age (P