Whole Genome Sequencing in the Undergraduate Classroom: Outcomes and Lessons from a Pilot Course
Whole Genome Sequencing in the Undergraduate Classroom: Outcomes and Lessons from a Pilot Course
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DOI：
10.1128/jmbe.v9.89
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发表时间：
2008-05-01
影响因子：
1.9
通讯作者：
Triplett, Eric W.
中科院分区：
文献类型：
--
作者：
Drew, Jennifer C.;Triplett, Eric W.
生物2010报告要求本科院校为下一代研究人员做好准备，以适应日益整合先进技术、数字信息和大规模分析的生物学不断变化的方向。作为回应，佛罗里达大学微生物学和细胞科学系开发了一门研究型课程“细菌基因组测序”。“目标是通过对细菌基因组进行测序来教授本科生基因组学和原创性研究，通过撰写和提交项目结果来发展科学沟通技能，并促进对生物研究，特别是基因组学的兴趣。学生们一起工作，测序，组装和注释肠杆菌P101基因组。我们通过各种方法评估学生的学习、科学沟通技巧和学生的态度，包括考试、写作作业、口头报告、课程前和课程后调查以及最后的退出调查。评估结果表明学生的学习成果和对课程的积极态度。
The BIO2010 report challenged undergraduate institutions to prepare the next generation of researchers for the changing direction of biology that increasingly integrates advanced technologies, digital information, and large-scale analyses. In response, the Microbiology and Cell Science Department at the University of Florida developed a research-based course, "Bacterial Genome Sequencing." The objectives were to teach undergraduates about genomics and original research by sequencing a bacterial genome, to develop scientific communication skills by writing and submitting the project results as a class effort, and to promote an interest in biological research, particularly genomics. The students worked together to sequence, assemble, and annotate the Enterobacter cloacae P101 genome. We assessed student learning, scientific communication skills, and student attitudes by a variety of methods including exams, writing assignments, oral presentations, pre- and postcourse surveys, and a final exit survey. Assessment results demonstrate student learning gains and positive attitudes regarding the course.