Predictors of Reoperation After Sacral Neuromodulation: A Single Institution Evaluation of Over 400 Patients

Predictors of Reoperation After Sacral Neuromodulation: A Single Institution Evaluation of Over 400 Patients
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DOI:
10.1002/nau.22929
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发表时间:
2017-02-01
影响因子:
2
通讯作者:
Boura, Judith A.
Boura, Judith A.
中科院分区:
医学3区
文献类型:
--
作者:
Peters, Kenneth M.;Killinger, Kim A.;Boura, Judith A.

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目的:探讨骶神经调节(SNM)后可能导致患者再次手术的因素。方法:回顾我们纵向神经调节数据库中登记的患者。采用Pearson卡方检验、Fisher精确检验、Wilcoxon秩和检验和多变量logistic回归分析基线和3个月时的病历数据、排尿日记、间质性膀胱炎症状问题指数(ICSI-PI)和膀胱过度活动症(OAB-q)。结果如下:在407例患者中,134例(33%)在中位随访28.9个月(范围1.6-121.7)内至少接受了一次再次手术; 78/407例(19%)接受了翻修,56/407例(14%)接受了翻修。再次手术的最常见原因是缺乏疗效/症状恶化(n = 87)。再次手术组女性比例较高(P = 0.049),平均体重指数(BMI; P = 0.010)较低,重编程事件较多(P
Aims: To explore factors that may predispose patients to reoperation after sacral neuromodulation (SNM). Methods: Patients enrolled in our longitudinal neuromodulation database were reviewed. Medical records data, and voiding diaries, Interstitial Cystitis Symptom-Problem Indices (ICSI-PI), and Overactive Bladder Questionnaires (OAB-q) at baseline and 3 months were analyzed with Pearson's chi(2), Fisher's Exact test, Wilcoxon rank tests, and multivariable logistic regression. Results: Of 407 patients, 134 (33%) had at least one reoperation over median 28.9 months follow-up (range 1.6-121.7); 78/407 (19%) were revised, and 56/407 (14%) were explanted. The most common reason for reoperation was lack of efficacy/worsening symptoms (n = 87). The reoperations group had a higher proportion of women(P = 0.049), lower mean body mass index (BMI; P = 0.010), more reprogramming events (P