Gender-specific determinants of asthma among U.S. adults.
Gender-specific determinants of asthma among U.S. adults.
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DOI：
10.1186/s40733-017-0030-5
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发表时间：
2017-01-01
影响因子：
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通讯作者：
Himes, Blanca E
中科院分区：
文献类型：
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作者：
Greenblatt, Rebecca;Mansour, Omar;Himes, Blanca E
背景技术背景：哮喘是一种慢性呼吸道疾病，影响超过1870万美国成年人，在性别、种族/民族和社会经济地位方面存在显著差异。我们的目标是使用行为风险因素监测系统（BRFSS）和国家健康和营养检查调查（NHANES）的数据，确定美国成年人哮喘患病率的性别特异性人口统计学和社会经济学决定因素。进行了性别特异性回归分析，以建立哮喘患病率与年龄、种族/民族、收入、教育水平、吸烟状况结果：根据来自1，003，894名受访者的BRFSS数据，男性和女性的加权哮喘患病率分别为6.2%和10.6%。2级肥胖和3级肥胖与不超重或肥胖的女性相比，哮喘患病率分别高出2.5和3.5倍，而男性则高出1.7和2.4倍;目前与从不吸烟的女性相比，哮喘患病率高出1.4倍，而男性则高出1.1倍。从13，364名受访者的NHANES数据中获得了类似的结果：女性2级肥胖和3级肥胖与非超重或肥胖受访者的哮喘患病率分别高出2.0和3.3倍，尽管男性没有显著差异;女性目前与从不吸烟者的哮喘患病率高出1.8倍，男性没有显著差异。哮喘患病率的种族/民族和收入水平并没有显着差异，男性和女性之间。结论：我们的研究结果强调了肥胖和吸烟的重要性，可修改的哮喘危险因素，最强烈地影响妇女。
BACKGROUND: Asthma, a chronic respiratory disease affecting over 18.7 million American adults, has marked disparities by gender, race/ethnicity and socioeconomic status. Our goal was to identify gender-specific demographic and socioeconomic determinants of asthma prevalence among U.S. adults using data from the Behavioral Risk Factors Surveillance System (BRFSS) and the National Health and Nutrition Examination Survey (NHANES).METHODS: Gender-specific regression analyses were performed to model the relationship between asthma prevalence with age, race/ethnicity, income, education level, smoking status, and body mass index (BMI), while taking into account the study designs.RESULTS: Based on BRFSS data from 1,003,894 respondents, weighted asthma prevalence was 6.2% in males and 10.6% in females. Asthma prevalence among grade 2 obese and grade 3 obese vs. not overweight or obese women was 2.5 and 3.5 times higher, respectively, while that in men was 1.7 and 2.4 times higher; asthma prevalence among current vs. never smoker women was 1.4 times higher, while that in men was 1.1 times higher. Similar results were obtained with NHANES data from 13,364 respondents: asthma prevalence among grade 2 obese and grade 3 obese vs. not overweight or obese respondents was 2.0 and 3.3 times higher for women, though there was no significant difference for men; asthma prevalence among current vs. never smokers was 1.8 times higher for women and not significantly different in men. Asthma prevalence by race/ethnicity and income levels did not differ considerably between men and women.CONCLUSIONS: Our results underscore the importance of obesity and smoking as modifiable asthma risk factors that most strongly affect women.