Modeling of human colonic blood flow for a novel artificial anal sphincter system

Modeling of human colonic blood flow for a novel artificial anal sphincter system
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新型人工肛门括约肌系统的人体结肠血流建模

DOI:
10.1631/jzus.b0820099
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发表时间:
2008-08
影响因子:
5.1
通讯作者:
Yan, Guo-Zheng
Yan, Guo-Zheng
中科院分区:
生物学2区
文献类型:
--
作者:
Liu, Hua;Zan, Peng;Yan, Guo-Zheng

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A novel artificial anal sphincter system has been developed to simulate the normal physiology of the human anorectum. With the goal of engineering a safe and reliable device, the model of human colonic blood flow has been built and the relationship between the colonic blood flow rate and the operating occlusion pressure of the anorectum is achieved. The tissue ischemia is analyzed based on constitutive relations for human anorectum. The results suggest that at the planned operating occlusion pressure of less than 4 kPa the artificial anal sphincter should not risk the vascularity of the human colon.
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