Quantitative laser speckle auto-inverse covariance imaging for robust estimation of blood flow
Quantitative laser speckle auto-inverse covariance imaging for robust estimation of blood flow
复制标题
定量激光散斑自逆协方差成像可稳健估计血流
DOI：
10.1364/ol.422062
复制
发表时间：
2021-05-15
期刊：
影响因子：
3.6
通讯作者：
Li, Pengcheng
中科院分区：
文献类型：
--
作者：
Hong, Jiachi;Zhu, Xuan;Li, Pengcheng
We present a quantitative model to provide robust estimation of the decorrelation time using laser speckle auto-inverse covariance. It has the advantages of independence from the statistical sample size, speckle size, static scattering, and detector noise. We have shown cerebral blood flow imaging through an intact mouse skull using this model. Phantom experiments and two animal models, middle cerebral artery occlusion, and cortical spreading depression were used to evaluate its performance. (C) 2021 Optical Society of America
