Diffraction phase microscopy for quantifying cell structure and dynamics
Diffraction phase microscopy for quantifying cell structure and dynamics
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DOI：
10.1364/ol.31.000775
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发表时间：
2006-03-15
期刊：
影响因子：
3.6
通讯作者：
Feld, MS
中科院分区：
文献类型：
--
作者：
Popescu, G;Ikeda, T;Feld, MS
我们发展了衍射位相显微镜作为生物结构定量位相成像的一种新技术。该方法结合了共光路干涉和单炮相位成像的原理，具有亚纳米光程稳定性和毫秒级捕获时间的特点。通过对红细胞的实验证明了这种技术在活细胞中量化纳米级运动的潜力。(C)2006年美国光学学会。
We have developed diffraction phase microscopy as a new technique for quantitative phase imaging of biological structures. The method combines the principles of common path interferometry and single-shot phase imaging and is characterized by subnanometer path-length stability and millisecond-scale acquisition time. The potential of the technique for quantifying nanoseale motions in live cells is demonstrated by experiments on red blood cells. (c) 2006 Optical Society of America.