STATIC AND DYNAMIC-RESPONSES OF PERIODONTAL-LIGAMENT MECHANORECEPTORS AND INTRADENTAL MECHANORECEPTORS
STATIC AND DYNAMIC-RESPONSES OF PERIODONTAL-LIGAMENT MECHANORECEPTORS AND INTRADENTAL MECHANORECEPTORS
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DOI：
10.1152/jn.1993.69.5.1567
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发表时间：
1993-05-01
影响因子：
2.5
通讯作者：
CHUDLER, EH
中科院分区：
文献类型：
--
作者：
DONG, WK;SHIWAKU, T;CHUDLER, EH
1.采用细胞外记录方法从同侧三叉半月神经节中分离出与完整下颌尖牙相关的39个牙周膜机械感受器(PDLM)和12个牙内机械感受器(IM)的反应特性。2．单个 PDLM 的刺激阈值和响应幅度取决于施加到完整犬牙的稳定力的方向。然而，犬类 PDLM 作为一个群体并没有首选的刺激方向。 IM 只能通过向任何方向施加到完整牙齿的快速机械瞬变来激活。每个IM的刺激阈值和反应幅度在所有刺激方向上大致等价。 3．可量化的斜坡和保持刺激的应用表明，PDLM 可以对稳定力的强度以及力斜坡的速率进行编码。增加斜坡速率会减少总斜坡放电，但会增加峰值放电频率。 IM 仅编码通过敲击施加的力斜坡的速率。较高的斜坡率增加了 IMs.4 的总放电量和峰值放电频率。正弦振动刺激可以清楚地区分 PDLM 和 IM 的动态响应特性。在刺激周期长度（251 +/- 103 Hz，平均值 +/- SD）和任何周期（包括刺激周期长度的倍数（295 +/- 100 Hz））下 IM 放电夹带的最大频率显着高于在刺激周期长度（103 +/-53 Hz）和任何周期（133 +/- 62 Hz）下 PDLM 放电夹带的最大频率。5。讨论了 PDLM 和 IM 分别与皮肤中缓慢适应 II 型机械感受器和 Pacinian 小体受体的功能相似性。我们目前的研究结果补充了早期的解剖学和行为证据，强烈表明 IM 有助于非伤害性和非疼痛功能。 PDLM 和 IM 都可以提供牙齿触觉所需的连续动态传入输入。
1. The response properties of 39 periodontal ligament mechanoreceptors (PDLMs) and 12 intradental mechanoreceptors (IMs) related to the intact mandibular canine tooth were isolated by extracellular recording methods from the ipsilateral trigeminal semilunar ganglion.2. The stimulus threshold and response magnitude of individual PDLMs depended on the direction of steady force applied to the intact canine tooth. Canine PDLMs as a population, however, did not have a preferred stimulus direction. IMs were activated only by a rapid mechanical transient applied to the intact tooth in any direction. The stimulus threshold and response magnitude of each IM were approximately equipotent in all stimulus directions.3. Application of quantifiable ramp-and-hold stimulation showed that PDLMs can encode the intensity of steady forces as well as the rate of force ramps. Increasing the ramp rates decreased the total ramp discharge but increased the peak discharge frequency. IMs encoded only the rate of force ramps that were applied by percussion. Higher ramp rates increased both the total discharges and peak discharge frequency of IMs.4. The dynamic response properties of PDLMs and IMs were clearly differentiated by sinusoidal vibratory stimulation. The maximum frequencies for entrainment of IM discharge at the stimulus cycle length (251 +/- 103 Hz, mean +/- SD) and at any periodicity including multiples of the stimulus cycle length (295 +/- 100 Hz) were significantly higher than the maximum frequencies for PDLM discharge entrainment at the stimulus cycle length (103 +/-53 Hz) and at any periodicity (133 +/- 62 Hz).5. The functional similarities of PDLMs and IMs, respectively, to slowly adapting type II mechanoreceptors and Pacinian corpuscle receptors in the skin are discussed. Our present findings, which complement earlier anatomic and behavioral evidence, strongly suggest that IMs subserve nonnociceptive and nonpain functions. Both PDLMs and IMs may provide a continuum of dynamic afferent inputs necessary for tactile sensibility of teeth.