Evaluation of a Generative Adversarial Network to Improve Image Quality and Reduce Radiation-Dose during Digital Breast Tomosynthesis.
Evaluation of a Generative Adversarial Network to Improve Image Quality and Reduce Radiation-Dose during Digital Breast Tomosynthesis.
复制标题
DOI：
10.3390/diagnostics12020495
复制
发表时间：
2022-02-14
期刊：
影响因子：
--
通讯作者：
Koibuchi Y
中科院分区：
文献类型：
--
作者：
Gomi T;Kijima Y;Kobayashi T;Koibuchi Y
在这项研究中，我们评估了在低辐射剂量条件下使用条件生成对抗网络[cGAN(Pix2pix)]进行预重建处理的数字乳腺断层合成中图像质量的改善。比较了Pix2Pix滤波反投影法(FBP)和多尺度双侧滤波法(MSBF)在预重建过程中的应用。使用BR3D模型，在不同的辐射剂量[参考剂量(自动曝光控制参考剂量：AECrd)、AECrd的50%和75%减少]和模型厚度(40 mm、50 mm和60 mm)下，使用焦点平面上的全宽半高宽(FWHM)、对比度噪声比(CNR)、峰值信噪比(PSNR)和结构相似性(SSIM)来比较降噪和保持对比度的比率。在半高宽、PSNR和SSIM方面，Pix2Pix预重建处理的整体性能是有效的。在大约50%的辐射剂量减少时，FWHM产生了良好的结果，与BR3D模型中使用的微钙化大小无关，并且良好的降噪和保持对比度。PSNR结果表明，在辐射剂量减少约50%的情况下，与参考FBP图像相比，Pix2Pix预重建处理的误差最小。SSIM分析表明，在辐射剂量减少约50%的情况下，与未进行MSBF预重建处理相比，Pix2Pix预重建处理获得了更好的相似性，其特征与参考FBP图像最相似。因此，在保持对比度和降低辐射剂量的情况下，Pix2pix预重建处理在临床应用中具有很好的降噪效果。
In this study, we evaluated the improvement of image quality in digital breast tomosynthesis under low-radiation dose conditions of pre-reconstruction processing using conditional generative adversarial networks [cGAN (pix2pix)]. Pix2pix pre-reconstruction processing with filtered back projection (FBP) was compared with and without multiscale bilateral filtering (MSBF) during pre-reconstruction processing. Noise reduction and preserve contrast rates were compared using full width at half-maximum (FWHM), contrast-to-noise ratio (CNR), peak signal-to-noise ratio (PSNR), and structural similarity (SSIM) in the in-focus plane using a BR3D phantom at various radiation doses [reference-dose (automatic exposure control reference dose: AECrd), 50% and 75% reduction of AECrd] and phantom thicknesses (40 mm, 50 mm, and 60 mm). The overall performance of pix2pix pre-reconstruction processing was effective in terms of FWHM, PSNR, and SSIM. At ~50% radiation-dose reduction, FWHM yielded good results independently of the microcalcification size used in the BR3D phantom, and good noise reduction and preserved contrast. PSNR results showed that pix2pix pre-reconstruction processing represented the minimum in the error with reference FBP images at an approximately 50% reduction in radiation-dose. SSIM analysis indicated that pix2pix pre-reconstruction processing yielded superior similarity when compared with and without MSBF pre-reconstruction processing at ~50% radiation-dose reduction, with features most similar to the reference FBP images. Thus, pix2pix pre-reconstruction processing is promising for reducing noise with preserve contrast and radiation-dose reduction in clinical practice.
登录
查看更多内容
DOI：
10.3390/diagnostics11091629
发表时间：
2021-09-06
期刊：
Diagnostics (Basel, Switzerland)
影响因子：
--
作者：
Gomi T;Sakai R;Hara H;Watanabe Y;Mizukami S
通讯作者：
Mizukami S
影响因子：
1.8
作者：
Bleuet, P;Guillemaud, R;Magnin, I
通讯作者：
Magnin, I
影响因子：
2
作者：
GORDON, R;BENDER, R;HERMAN, GT
通讯作者：
HERMAN, GT
影响因子：
3.8
作者：
Lu, Yao;Chan, Heang-Ping;Samala, Ravi K.
通讯作者：
Samala, Ravi K.
影响因子：
10.6
作者：
Samala, Ravi K.;Chan, Heang-Ping;Cha, Kenny H.
通讯作者：
Cha, Kenny H.