Estimated GFR and Fracture Risk: A Population-Based Study
Estimated GFR and Fracture Risk: A Population-Based Study
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DOI：
10.2215/cjn.09130912
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发表时间：
2013-07-31
影响因子：
9.8
通讯作者：
Hemmelgarn, Brenda R.
中科院分区：
文献类型：
--
作者：
Elliott, Meghan J.;James, Matthew T.;Hemmelgarn, Brenda R.
背景和目的尽管终末期肾病患者的骨折风险高于普通人群，但关于慢性肾脏病患者的骨折发生率仍存在相互矛盾的证据。本研究旨在确定估计GFR（eGFR）和骨折率之间的关联。设计，设置，参与者和测量本研究确定了1，815，943名社区居民成年人，他们在2002年至2008年期间至少有一次门诊血清肌酐测量。的eGFR患者
Background and objectives Although patients with ESRD have a higher fracture risk than the general population, there is conflicting evidence regarding fracture incidence in those with CKD. This study sought to determine the association between estimated GFR (eGFR) and fracture rates.Design, setting, participants, & measurements This study identified 1,815,943 community-dwelling adults who had at least one outpatient serum creatinine measurement between 2002 and 2008. Patients with eGFR