Social (Pragmatic) Communication Disorder: Another name for the Broad Autism Phenotype?
Social (Pragmatic) Communication Disorder: Another name for the Broad Autism Phenotype?
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DOI：
10.1177/1362361318822503
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发表时间：
2019-11-01
期刊：
影响因子：
5.2
通讯作者：
Brzustowicz, Linda
中科院分区：
文献类型：
--
作者：
Flax, Judy;Gwin, Christine;Brzustowicz, Linda
《精神障碍诊断与统计手册》（第5版）社会（语用）沟通障碍旨在捕捉不符合自闭症谱系障碍标准的儿童沟通障碍的社会因素。目前尚不清楚社交（语用）沟通障碍是否与自闭症谱系障碍或精神障碍诊断与统计手册（第5版）语言障碍重叠，而不包含这些因素。在一项家庭遗传学研究中，采用标准化行为评估来评估自闭症谱系障碍、语言障碍或无自闭症谱系障碍的人的社会沟通障碍、限制兴趣和重复行为。社会沟通障碍与兴趣限制、重复行为在所有家庭成员中均显著相关。自闭症谱系障碍患者的社会沟通障碍、兴趣限制和重复行为发生率最高。三分之一有语言障碍的家庭成员表现出轻度/中度以上的社交障碍（36.6%），兴趣受限和重复行为（43.3%）。一部分未受影响的成员也表现出轻度/中度的社会沟通障碍（父母= 10.1%，兄弟姐妹= 11.6%），兴趣受限和重复行为（父母= 14.0%，兄弟姐妹= 22.1%）。大多数轻度/中度社会沟通障碍的儿童家庭成员具有相似的限制兴趣和重复行为水平，反映了代表广泛自闭症表型的标准。这些数据表明，社会语用性沟通障碍并不能反映出既有社会沟通障碍又有兴趣限制和重复行为但需要临床服务的儿童的特征。
The Diagnostic and Statistical Manual of Mental Disorders' (5th ed.) Social (Pragmatic) Communication Disorder is meant to capture the social elements of communication dysfunction in children who do not meet autism spectrum disorder criteria. It is unclear whether Social (Pragmatic) Communication Disorder captures these elements without overlapping with Autism Spectrum Disorder or the Diagnostic and Statistical Manual of Mental Disorders' (5th ed.) Language Disorder. Standardized behavioral assessments administered during a family genetics study were used to evaluate the social communication impairment and the restricted interests and repetitive behaviors in persons with autism spectrum disorder, language impairment, or neither. Social communication impairment and restricted interests and repetitive behavior were significantly correlated in all family members regardless of affection status. Rates of social communication impairment and restricted interests and repetitive behavior were highest in individuals with autism spectrum disorder. One-third of family members with language impairment presented with at least mild/moderate levels of social communication impairment (36.6%) and restricted interests and repetitive behavior (43.3%). A subset of unaffected members also presented with mild/moderate levels of social communication impairment (parents = 10.1%, siblings 11.6%) and restricted interests and repetitive behavior (parents = 14.0%, siblings = 22.1%). The majority of child family members with mild/moderate levels of social communication impairment had similar restricted interest and repetitive behavior levels reflecting criteria representing the Broad Autism Phenotype. These data suggest that social pragmatic communication disorder does not capture the profiles of children who have both social communication impairment and restricted interests and repetitive behavior but are in need of clinical services.