Energy transfer in collisions of peptide ions with surfaces
Energy transfer in collisions of peptide ions with surfaces
复制标题
DOI：
10.1063/1.1589739
复制
发表时间：
2003-08-08
影响因子：
4.4
通讯作者：
Futrell, JH
中科院分区：
文献类型：
--
作者：
Laskin, J;Futrell, JH
利用单质子化八肽DES-Arg1-缓激肽的时间和能量分辨表面诱导解离(SID)研究了SID靶的物理性质对多肽离子与表面碰撞中平动能量转移效率(T->；V)的影响。本工作研究了四种不同化学成分和硬度的SID靶：1-十二烷硫醇(HSAM)及其氟化类似物(CF3(CF2)(9)C2H4SH-FSAM)在金表面的自组装单分子膜，抛光钛表面300 nm厚的氟化锂(LiF)层，以及钛表面2微米碳气相沉积的金刚石层。基于RRKM的建模方法被用来提取前驱体离子与不同表面碰撞时沉积到前驱体离子的内能分布。我们发现，T-->；V转移的比例依次增加：HSAM(10.1%)，LiF(12.0%)，钻石(19.2%)，FSAM(20.5%)。此外，能量沉积函数(EDF)的宽度受SID靶的性质影响。多肽离子与HSAM表面的碰撞导致相对较窄的内能分布的沉积，EDF的宽度按顺序增加：HSAM
Time- and energy-resolved surface induced dissociation (SID) of a singly protonated octapeptide des-Arg1-bradykinin was used to study the effect of physical properties of the SID target on the efficiency of translational to vibrational energy transfer (T-->V) in collisions of peptide ions with surfaces. Four SID targets of varying chemical composition and stiffness were examined in this work: self-assembled monolayers of 1-dodecane thiol (HSAM) and its fluorinated analog (CF3(CF2)(9)C2H4SH - FSAM) on gold, a 300 nm thick layer of lithium fluoride (LiF) on a polished titanium surface, and a 2 mum carbon vapor deposited diamond layer on a titanium surface. A RRKM-based modeling approach was utilized to extract internal energy distributions deposited into the precursor ion upon collisions with different surfaces. We found that the percent of T-->V transfer increases in the order: HSAM (10.1%), LiF (12.0%), diamond (19.2%), FSAM (20.5%). Furthermore, the width of the energy deposition function (EDF) is affected by the properties of the SID target. Collisions of peptide ions with the HSAM surface results in deposition of relatively narrow internal energy distributions with the width of the EDF increasing in the order: HSAM