COMPARISON OF CRITICAL PERIODS FOR MONOCULAR AND DIRECTIONAL DEPRIVATION IN CATS
COMPARISON OF CRITICAL PERIODS FOR MONOCULAR AND DIRECTIONAL DEPRIVATION IN CATS
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DOI：
10.1113/jphysiol.1977.sp011715
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发表时间：
1977-01-01
影响因子：
5.5
通讯作者：
DAW, NW
中科院分区：
文献类型：
--
作者：
BERMAN, N;DAW, NW
早期的实验表明，在一定年龄后闭眼饲养小猫，或者在一定年龄后闭眼饲养小猫，在旋转的鼓中饲养小猫，在旋转的鼓中饲养小猫，在旋转的鼓中饲养小猫，在旋转的鼓中饲养小猫，在旋转的鼓中饲养小猫，眼睛优势和方向敏感性的关键时期可能不同。对两种类型的视觉剥夺进行直接比较。饲养了四对同窝的小猫（体重相等）。每对动物中有一只被剥夺单眼，随后进行眼球翻转；另一种动物方向剥夺，鼓点方向反转。所有逆转发生在5周时。在给定的一对小猫中，两只小猫要么先向左（左眼先睁开或向左方向先睁开），要么都先向右。其中一人过早死亡。在4个月后的某个年龄从视觉皮层进行记录。一些记录在左皮层，一些记录在右皮层。在所有单眼剥夺的病例中，大多数细胞是由最后睁开的眼睛驱动的（即5周后睁开的眼睛）。在所有定向剥夺的情况下，大多数细胞倾向于在暴露的第一个方向上运动（即5周龄前的方向）。显然，定向剥夺的关键期比单眼剥夺的关键期终止得早。
Earlier experiments rearing kittens with 1 eye closed and reversing the closure after a certain age, or rearing kittens in a rotating drum and reversing the direction after a certain age, suggested that the critical periods for ocular dominance and directional sensitivity may differ. A direct comparison of the 2 types of visual deprivation was made. Four pairs of litter-mate kittens (matched in weight) were reared. One animal in each pair was monocularly deprived with subsequent eye reversal; the other animal was directionally deprived with reversal of drum direction. All reversals took place at age 5 wk. Both kittens in a given pair were either left first (left eye open first or left direction first) or both were right first. One died prematurely. Recordings were made from the visual cortex at some age after 4 mo. Some recordings were made in the left cortex and some in the right. In all cases of monocular deprivation, the majority of cells were driven by the eye that was open last (i.e., open after 5 wk of age). In all cases of directional deprivation, the majority of the cells preferred movement in the 1st direction of exposure (i.e., the direction before 5 wk of age). Apparently the critical period for directional deprivation terminates earlier than the critical period for monocular deprivation.