Three-dimensional ultrasound demonstration of the fetal palate in high-risk patients: the accuracy of prenatal visualization
Three-dimensional ultrasound demonstration of the fetal palate in high-risk patients: the accuracy of prenatal visualization
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DOI：
10.1002/pd.4083
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发表时间：
2013-05-01
影响因子：
3
通讯作者：
Achiron, Reuven
中科院分区：
文献类型：
--
作者：
Gindes, Liat;Weissmann-Brenner, Alina;Achiron, Reuven
Objective The aim of this research was to evaluate the ability of three-dimensional (3D) ultrasound for demonstrating the palate of fetuses at high risk for cleft palate. Method Fifty-seven fetuses at high risk for cleft palate were referred for specialist ultrasound at 1240weeks' gestation. A detailed assessment of palate was made using both two-dimensional and 3D ultrasounds on the axial plane. Antenatal diagnoses were compared with postnatal findings. Results Cleft palate was suspected in 13 (22.8%); a normal palate was demonstrated in 38 (67%), and in six (10.2%), the palate view could not be obtained. Mean gestational age at the first visit was 27weeks 6days (range of 1240weeks 3days). Examination after delivery revealed that one of the 38 fetuses with presumed normal palate had a cleft hard palate, and one had a cleft soft palate (false negative 5%). Among the 13 fetuses with suspected cleft palate, three had an intact palate (false-positive 23%). Sensitivity, specificity, positive predictive value, and negative predictive value of detection of palatal clefts were 71.4%, 91.9%, 62.5%, and 94.4%, respectively. Conclusion Using 3D technology, we diagnosed a cleft palate in 83% of high-risk cases, with 5% false negative. 3D technology might produce some technical artifacts resulting in a 23% false-positive rate. (c) 2013 John Wiley & Sons, Ltd.
