Mucoepidermoid carcinoma involving Warthin tumor. A report of five cases and review of the literature.
Mucoepidermoid carcinoma involving Warthin tumor. A report of five cases and review of the literature.
复制标题
粘液表皮样癌涉及 Warthin 瘤。
DOI：
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发表时间：
2000
影响因子：
3.5
通讯作者：
L. Medeiros
中科院分区：
文献类型：
--
作者：
J. Williamson;B. Simmons;A. El;L. Medeiros
我们报告5例粘液表皮样癌(MEC)合并腮腺沃辛瘤(WT)。肿瘤大小为1.7~6.0 cm。微血管内皮细胞小得多，为0.3~1.7厘米。3例WT完全包围MEC，2例WT和MEC均不包围另1例。所有MEC均为低级别，3例为I级，2例为II级。1例MEC有血管侵犯。所有患者均行腮腺部分或次全切除术，切缘阴性。临床随访3例，8~52个月，无复发迹象。在这些病例中，WT和MEC之间的致病关系尚不确定。4例WT区可见鳞状上皮化生或粘液化生，3例伴有轻度细胞异型性。然而，没有确定从WT到MEC的直接过渡。1例MEC在WT前45个月出现，提示复发的MEC恰好累及WT。MEC体积小、级别低，切除切缘为负值，这很可能解释了这3名患者的良好预后，并有临床随访数据。
We describe 5 cases of mucoepidermoid carcinoma (MEC) involving Warthin tumor (WT) of the parotid gland. The WT size ranged from 1.7 to 6.0 cm. The MECs were much smaller, 0.3 to 1.7 cm. In 3 cases, the WT completely surrounded the MEC, and in 2 cases neither WT nor MEC surrounded the other. Each MEC was low grade, 3 grade I and 2 grade II. One MEC had evidence of vascular invasion. All patients underwent partial or subtotal parotidectomy with negative resection margins. Clinical follow-up (range, 8-52 months) for 3 patients showed no evidence of recurrence. The pathogenetic relationship between WT and MEC in these cases is uncertain. In 4 cases, foci of squamous or mucous metaplasia were found in the WT component, associated with mild cytologic atypia in 3 tumors. However, a direct transition from WT to MEC was not identified. In 1 case, MEC was present 45 months before WT, suggesting that the recurrent MEC involved WT coincidentally. The small size and low grade of the MEC and the negative resection margins most likely explain the good outcome for the 3 patients with clinical follow-up data available.
既往接受儿童癌症治疗的患者的恶性腮腺肿瘤：八例临床和影像学结果。
DOI：
10.2214/ajr.162.3.8109517
发表时间：
1994
期刊：
AJR. American journal of roentgenology
影响因子：
--
作者：
Kaste,SC;Hedlund,G;Pratt,CB
通讯作者：
Pratt,CB