Anatomy and Physiology of the Right Ventricle

Anatomy and Physiology of the Right Ventricle
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DOI:
10.1016/j.ccl.2012.03.009
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发表时间:
2012-05-01
期刊:
影响因子:
2.4
通讯作者:
Dell'Italia, Louis J.
Dell'Italia, Louis J.
中科院分区:
医学4区
文献类型:
--
作者:
Dell'Italia, Louis J.

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在正常基线条件下,右心室(RV)独特的解剖结构、心肌超微结构和冠状动脉生理学反映了一个大容量低压泵。早期的工作将RV描述为具有最小泵送能力的被动导管。现在认识到,通过心室相互依赖的机制,左室收缩功能和舒张负荷在充血性心力衰竭、心脏移植、肺动脉高压、先天性心脏病和左心室辅助装置的预后和治疗中非常重要。磁共振成像与三维分析显示了复杂的几何RV和两个心室在心包内的相互作用。
Under normal baseline conditions the unique anatomy, myocardial ultrastructure, and coronary physiology of the right ventricle (RV) reflect a high-volume low-pressure pump. Early work described the RV as a passive conduit with minimal pumping capability. It is now appreciated that through a mechanism of ventricular interdependence, RV systolic function and diastolic load are extremely important in the prognosis and treatment of congestive heart failure, cardiac transplantation, pulmonary hypertension, congenital heart disease, and left ventricle assist devices. Magnetic resonance imaging with three-dimensional analysis has shown the complex geometry of the RV and the interaction of both ventricles within the pericardium.