Electrocatalytic Tandem Synthesis of 1,3-Disubstituted Imidazo[1,5-a]quinolines via Sequential Dual Oxidative C(sp3)-H Amination in Aqueous Medium
Electrocatalytic Tandem Synthesis of 1,3-Disubstituted Imidazo[1,5-a]quinolines via Sequential Dual Oxidative C(sp3)-H Amination in Aqueous Medium
复制标题
水介质中连续双氧化 C(sp3)-H 胺化电催化串联合成 1,3-二取代咪唑并[1,5-a]喹啉
DOI：
10.1021/acs.joc.8b03014
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发表时间：
2019-03-15
影响因子：
3.6
通讯作者：
Wang, Zhiyong
中科院分区：
文献类型：
--
作者：
Qian, Peng;Yan, Zicong;Wang, Zhiyong
以水溶液为介质，以易得的原料为起始原料，采用NH 4 I介导串联电合成1，3-二取代咪唑并[1，5-a]喹啉类化合物，得到了多种1，3-二取代咪唑并[1，5-a]喹啉类化合物。
An NH4I-mediated tandem electrosynthesis of 1,3-disubstituted imidazo[1,5-a]quinolines was developed from readily available starting materials in aqueous medium, affording a variety of 1,3-disubstituted imidazo[1,5-a]quinolines with good to excellent yields.