Voucher-based reinforcement of opiate plus cocaine abstinence in treatment-resistant methadone patients: Effects of reinforcer magnitude

Voucher-based reinforcement of opiate plus cocaine abstinence in treatment-resistant methadone patients: Effects of reinforcer magnitude
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DOI:
10.1037/1064-1297.9.3.317
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发表时间:
2001-08-01
影响因子:
2.3
通讯作者:
Stitzer, ML
Stitzer, ML
中科院分区:
医学3区
文献类型:
--
作者:
Dallery, J;Silverman, K;Stitzer, ML

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该研究测试了基于代金券的戒断强化程序,以减少对治疗有抵抗力的阿片类和可卡因滥用美沙酮患者群体中阿片类和可卡因的使用。可兑换商品和服务的代金券取决于戒除阿片类药物和可卡因的情况。在两种情况下,参与者提供不含阿片类和可卡因的尿样可赚取高达 374 美元或 3,369 美元的代金券。参与者每天接受 60 毫克剂量的美沙酮。第二阶段增加了剂量,并复制了凭证条件。两个阶段的分析揭示了在高券条件下更多禁欲的趋势,并表明更高的剂量可能会增强券强化的功效。结果表明,即使在治疗耐药人群中,同时强化戒断两种药物也能有效。
The study tested a voucher-based abstinence reinforcement procedure for reducing opiate and cocaine use in a population of treatment-resistant opiate- and cocaine-abusing methadone patients. Vouchers exchangeable for goods and services were contingent on abstinence from both opiates and cocaine, In two conditions, participants could earn up to $374 or $3,369 in vouchers for providing opiate- and cocaine-free urine samples. Participants received a daily 60-mg dose of methadone. The dose was increased in a second phase, and the voucher conditions were replicated. Analyses of both phases revealed trends toward greater abstinence under the high voucher condition and suggested that higher doses may enhance the efficacy of voucher reinforcement. The results show that reinforcement for abstinence from 2 drugs simultaneously can be effective even in a treatment-resistant population.