National estimates of blood lead, cadmium, and mercury levels in the Korean general adult population
National estimates of blood lead, cadmium, and mercury levels in the Korean general adult population
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DOI：
10.1007/s00420-010-0522-6
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发表时间：
2011-01-01
影响因子：
3
通讯作者：
Lee, Byung-Kook
中科院分区：
文献类型：
--
作者：
Kim, Nam-Soo;Lee, Byung-Kook
ObjectiveTo assess the extent of exposure to lead，cadmium，and mercury in the Korean general adult population using a representative sampling.Methods我们研究了三种重金属的血液浓度在一个有代表性的样本的1，997韩国人作为第三次韩国国民健康和营养检查调查的一部分结果血铅、镉、汞浓度的几何平均值分别为2.61 μ g/dL、1.53 μ g/L、4.15 μ g/L，[95%置信区间（CI）分别为2.50-2.71、1.48-1.58和3.94-4.36]。在校正和未校正的分析中，女性血铅和汞浓度显着降低，但在血镉分析中没有观察到性别差异。年龄大于40岁的受试者血铅和汞水平的几何平均值高于年龄小于40岁的受试者。吸烟状况只影响血铅浓度，吸烟者的血铅浓度高于非吸烟者。经协变量调整后，血镉水平与人口统计学和生活方式变量无差异。血汞浓度较高，在那些谁消耗酒精，也增加了与频率的鱼consumption.Conclusions的血液重金属在韩国一般人群的KNHANES III的一部分，这生物监测研究提供了重要的参考数据分层的人口和生活方式因素，将是有用的，为正在进行的监测韩国一般人群的环境暴露于重金属。
Objectives To assess the extent of exposure to lead, cadmium, and mercury in the Korean general adult population using a representative sample.Methods We studied blood concentrations of three heavy metals in a representative sample of 1,997 Koreans as part of the Third Korean National Health and Nutrition Examination Survey (KNHANES III) performed in 2005.Results The geometric means of the blood lead, cadmium, and mercury concentrations were 2.61 mu g/dL, 1.53 mu g/L, and 4.15 mu g/L, respectively [95% confidence intervals (CIs), 2.50-2.71, 1.48-1.58, and 3.94-4.36, respectively]. Women had significantly lower blood lead and mercury concentrations in adjusted and unadjusted analyses but no difference between genders was observed in blood cadmium analysis. The geometric means of blood lead and mercury levels were higher in subjects older than 40 years than in those younger than 40 years. Smoking status only affected the blood lead concentration, with this being higher in smokers than in nonsmokers. Blood cadmium levels did not differ with demographic and lifestyle variables after covariate adjustment. Blood mercury concentrations were higher in those who consumed alcohol and also increased with the frequency of fish consumption.Conclusions This biomonitoring study of blood heavy metals in the Korean general population as part of KNHANES III provides important reference data stratified by demographic and lifestyle factors that will be useful for the ongoing surveillance of environmental exposure of the Korean general population to heavy metals.