Intraindividual Variability in Daily Sleep and Pain Ratings Among Chronic Pain Patients: Bidirectional Association and the Role of Negative Mood
Intraindividual Variability in Daily Sleep and Pain Ratings Among Chronic Pain Patients: Bidirectional Association and the Role of Negative Mood
复制标题
DOI：
10.1097/ajp.0b013e318208c8e4
复制
发表时间：
2011-06-01
影响因子：
2.9
通讯作者：
Robinson, Michael E.
中科院分区：
文献类型：
--
作者：
O'Brien, Erin M.;Waxenberg, Lori B.;Robinson, Michael E.
目的：睡眠障碍是慢性疼痛患者的常见问题。来自临床人群和实验研究的横截面数据表明睡眠障碍和疼痛之间存在关联。然而，很少有前瞻性的研究到睡眠和疼痛之间的日常变化之间的关系在慢性pain patients.Methods：22名妇女与慢性疼痛（背痛，面部疼痛，纤维肌痛）完成了睡眠日记，戴活动记录仪为2周的时间。疼痛、情绪和睡眠的自我报告测量也在基线完成。分层线性模型（HLM）被用来检查这些妇女的睡眠和疼痛评级的个体内变异。情绪和基线疼痛评级的影响也被检查为潜在的moderators.Results：分层线性模型分析支持睡眠和疼痛之间的双向关系，如一个晚上的睡眠不好，其次是增加疼痛评级的第二天，一天的疼痛增加，其次是一个晚上的睡眠不好。抑郁评分进一步影响这些relationships.Discussion：前瞻性研究支持一组慢性疼痛的女性之间的睡眠和疼痛的双向关系。抑郁症状对这些关系有调节作用。这些发现表明，解决睡眠问题在治疗慢性疼痛患者中非常重要。
Objectives: Sleep disturbance is a common problem among chronic pain patients. Cross-sectional data from clinical populations and experimental studies have shown an association between sleep disturbance and pain. However, there has been little prospective research into the relationship between daily variability between sleep and pain among chronic pain patients.Methods: Twenty-two women with chronic pain (back pain, facial pain, fibromyalgia) completed a sleep diary and wore an actigraph for a 2-week period. Self-report measures of pain, mood, and sleep were also completed at baseline. Hierarchical linear modeling (HLM) was used to examine intraindividual variability in sleep and pain ratings among these women. The impact of mood and baseline pain ratings was also examined as potential moderators.Results: Hierarchical linear modeling analyses supported a bidirectional relationship between sleep and pain, such that a night of poor sleep was followed by increased pain ratings the following day and a day of increased pain was followed by a night of poor sleep. Depression scores further influenced these relationships.Discussion: Prospective examination supported a bidirectional relationship between sleep and pain among a group of women with chronic pain. Depressive symptoms had a moderating impact on these relationships. These findings suggest that addressing sleep is important in the treatment of individuals with chronic pain.