Prognostic Value of the Sixth Edition of the UICC's TNM Classification and Stage Grouping for Oral Cancer
Prognostic Value of the Sixth Edition of the UICC's TNM Classification and Stage Grouping for Oral Cancer
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DOI：
10.1002/jso.21547
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发表时间：
2010-10-01
影响因子：
2.5
通讯作者：
Scheer, Martin
中科院分区：
文献类型：
--
作者：
Kreppel, Matthias;Eich, Hans Theodor;Scheer, Martin
背景资料：口腔癌根据UICC的TNM分期系统进行分类，该分期系统正在不断修订中。我们的研究目的是评估2003年建立的UICC第六版对口腔癌的预后价值。回顾性分析了300例未经治疗的I-IVb期口腔鳞状细胞癌（OSCC）患者，结果：单因素分析显示T分期（P = 0.009）、N分期（P <0.001）对预后有显著影响。和UICC阶段（P
Background: Carcinoma of the oral cavity is classified according to the TNM staging system of the UICC The staging system is under continuous revision The aim of our study was to assess the prognostic value of the UICC sixth edition for oral cancer, which was established in 2003Methods: Three-hundred treatment-naive patients with oral squamous cell carcinoma (OSCC) of stages I-IVb were reviewed retrospectively Patients with stage-I disease were treated solely surgically, and patients with stage II-IVb received a multi modal treatment Overall survival was plotted by Kaplan-Meier analysis Prognostic factors were identified through univariate and multivariate analysisResults: Univariate analysis showed a significant impact of T stage (P = 0 009), N stage (P < 0 001). and UICC stage (P