Nosocomial infections in a Brazilian neonatal intensive care unit: a 4-year surveillance study
Nosocomial infections in a Brazilian neonatal intensive care unit: a 4-year surveillance study
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DOI：
10.1590/s0037-86822010000600006
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发表时间：
2010-12-01
影响因子：
2
通讯作者：
Gontijo Filho, Paulo Pinto
中科院分区：
文献类型：
--
作者：
Brito, Denise Von Dollinger;Brito, Cristiane Silveira de;Gontijo Filho, Paulo Pinto
简介：报告Uberlandia大学医院新生儿重症监护病房院内感染的发生率、致病微生物、相关危险因素和抗菌药物敏感性模式。方法.数据通过2006年1月至2009年12月的国家医疗保健安全网络监测收集。从出生到出院或死亡，每周对患者进行5次随访。结果该研究包括1，443名患者，其中209名发生NI，共计293次NI发作，主要是血流感染（203; 69.3%）和结膜炎（52; 17.7%）。器械相关感染率如下：17.3例原发性血流感染/1000个中心静脉导管-日，3.2例肺炎/1000个呼吸机-日。新生儿医院感染病死率为11.9%。机械通气、全胃肠外营养、口胃管、既往抗生素治疗、使用CVC和出生体重751- 1000 g似乎与NI风险显著升高相关（p
Introduction: Report the incidence of nosocomial infections, causative microorganisms, risk factors associated with and antimicrobial susceptibility pattern in the NICU of the Uberlandia University Hospital. Methods. Data were collected through the National Healthcare Safety Network surveillance from January 2006 to December 2009. The patients were followed five times/week from their birth to their discharge or death. Results. The study included 1,443 patients, 209 of these developed NIs, totaling 293 NI episodes, principally bloodstream infections (203; 69.3%) and conjunctivitis (52; 17.7%). Device-associated infection rates were as follows: 17.3 primary bloodstream infections per 1,000 central line-days and 3.2 pneumonias per 1000 ventilator-days. The mortality rate in neonates with NI was 11.9%. Mechanical ventilation, total parenteral nutrition, orogastric tube, previous antibiotic therapy, use of CVC and birth weight of 751-1,000g appeared to be associated with a significantly higher risk of NI (p