Preemptive Local Anesthetic in Gynecologic Laparoscopy and Postoperative Movement-Evoked Pain: A Randomized Trial
Preemptive Local Anesthetic in Gynecologic Laparoscopy and Postoperative Movement-Evoked Pain: A Randomized Trial
复制标题
DOI：
10.1016/j.jmig.2016.03.009
复制
发表时间：
2016-07-01
影响因子：
4.1
通讯作者：
Vandrevala, Tushna
中科院分区：
文献类型：
--
作者：
Ravndal, Caroline;Vandrevala, Tushna
研究目的：评价在腹腔镜妇科手术中，在增强恢复计划（ERP）中，预先将局麻药注射到套管针区域是否可减少术后运动诱发疼痛。设计：一项平行分配的随机双盲试验（加拿大工作组分类I）。设置：研究在挪威斯塔万格的斯塔万格大学医院的妇科进行。患者：24名妇女符合择期腹腔镜手术的良性适应症内的ERP被included.Interventions：妇女被随机分配到先发制人的局部注射0.5%布比卡因，（干预组）或0.9%生理盐水测量和主要结果：本研究的主要结果测量是手术后5小时的运动诱发疼痛。次要结局指标为术后2小时和5小时休息时的疼痛以及术后期间急救镇痛药的使用。根据0 - 10的数字评定量表测量疼痛。数据进行了符合方案分析，
Study Objective: To evaluate whether preemptive local anesthetics injected into the trocar areas reduce postoperative movement-evoked pain within an enhanced recovery program (ERP) in laparoscopic gynecologic surgery.Design: A randomized and double-blinded trial with parallel assignments (Canadian Task Force Classification I).Setting: The study was conducted in the gynecologic department at the University Hospital of Stavanger, Stavanger, Norway.Patients: Twenty-four women eligible for elective laparoscopic surgery for a benign indication within an ERP were included.Interventions: The women were randomized to preemptive local injections of either 0.5% bupivacaine (intervention group) or 0.9% saline (control group) at each trocar site.Measurements and Main Results: The primary outcome measure of the study was movement-evoked pain 5 hours after surgery. The secondary outcome measures were pain at rest 2 and 5 hours after surgery and the use of rescue analgesics during the postoperative period. Pain was measured on a numeric rating scale of 0 to 10. Data were treated to a per-protocol analysis, and a p