Population Genetics Theory - The Past and the Future
Population Genetics Theory - The Past and the Future
复制标题
群体遗传学理论——过去与未来
DOI：
10.1007/978-94-009-0513-9_4
复制
发表时间：
1990
影响因子：
10.7
通讯作者：
W. Ewens
中科院分区：
文献类型：
--
作者：
W. Ewens
经典的群体遗传学理论主要针对与未来有关的过程。相比之下，目前的理论关注的是过去，尤其是想要对进化过程做出推断的愿望，这些进化过程导致了目前观察到的遗传变异的模式和性质。经典的前瞻性理论与新的回顾性理论之间有许多联系。然而，回溯理论引入了经典理论中没有出现的观点，特别是那些关于样本或整个群体中基因的祖先的观点。它还在科学文献中引入了两个重要的新分布，即泊松-狄利克雷分布和GEM分布：它们不仅在群体遗传学中很重要，而且在科学和数学的广泛领域中也很重要。本文讨论了其中一些问题。由于引入了许多与过去生物种群进化有关的新概念，种群遗传学理论得到了极大的丰富。
Classical population genetics theory was largely directed towards processes relating to the future. Present theory, by contrast, focuses on the past, and in particular is motivated by the desire to make inferences about the evolutionary processes which have led to the presently observed patterns and nature of genetic variation. There are many connections between the classical prospective theory and the new retrospective theory. However, the retrospective theory introduces ideas not appearing in the classical theory, particularly those concerning the ancestry of the genes in a sample or in the entire population. It also introduces two important new distributions into the scientific literature, namely the Poisson-Dirichlet and the GEM: these are important not only in population genetics, but also in a very wide range in science and mathematics. Some of these are discussed. Population genetics theory has been greatly enriched by the introduction of many new concepts relating to the past evolution of biological populations.