Isolated Extracranial Recurrence of Anaplastic Ependymoma
Isolated Extracranial Recurrence of Anaplastic Ependymoma
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DOI：
10.1002/pbc.22764
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发表时间：
2011-02-01
影响因子：
3.2
通讯作者：
Rood, Brian R.
中科院分区：
文献类型：
--
作者：
Chao, Mwe Mwe;Packer, Roger J.;Rood, Brian R.
间变性室管膜瘤是一种恶性神经胶质瘤，被认为起源于心室区的放射状神经胶质细胞。由于室管膜瘤常见于脑室内，因此很容易发生软脑膜播散。转移性颅外室管膜瘤已有报道，但发生在进行性颅内疾病的背景下。我们报道了一名男孩的间变性室管膜瘤出现颅外孤立性复发，最初发生在头皮，后来转移到颈部淋巴结。肿瘤复发位置靠近手术部位提示手术种植。该病例展示了间变性室管膜瘤的不寻常复发部位，并强调了以前未被充分认识的手术并发症。儿童血癌。 2011；56：317-318。 (C) 2010 Wiley-Liss, Inc.
Anaplastic ependymoma is a malignant glial tumor thought to arise from radial glial cells of the ventricular zone. Because ependymoma is frequently encountered within ventricular spaces, they are prone to leptomeningeal dissemination. Metastatic extracranial ependymoma has been reported, but in the context of progressive intracranial disease. We report on a boy who developed isolated extracranial recurrence of his anaplastic ependymoma, initially at the scalp and later metastases to cervical lymph nodes. The location of tumor recurrence proximate to the surgical site suggested surgical seeding. This case demonstrates an unusual site of recurrence of anaplastic ependymoma and highlights a previously underappreciated surgical complication. Pediatr Blood Cancer. 2011;56:317-318. (C) 2010 Wiley-Liss, Inc.