THE ROLE OF ANXIETY AND DEPRESSION IN THE IRRITABLE-BOWEL-SYNDROME
THE ROLE OF ANXIETY AND DEPRESSION IN THE IRRITABLE-BOWEL-SYNDROME
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DOI：
10.1016/0005-7967(90)90159-g
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发表时间：
1990-01-01
影响因子：
4.1
通讯作者：
BARLOW, DH
中科院分区：
文献类型：
--
作者：
BLANCHARD, EB;SCHARFF, L;BARLOW, DH
使用可靠和有效的结构化诊断访谈量表（adi - r）和仔细的医学特征患者，我们发现在寻求治疗的肠易激综合征患者中，与寻求治疗的炎症性肠病患者的年龄和性别样本相比，显着增加了可诊断的精神病理学，特别是焦虑症。IBS患者与IBD患者及对照组在汉密尔顿焦虑评定量表和汉密尔顿抑郁评定量表上也存在显著差异，对照组无差异。在所有三组先证者的父母中都发现了相当水平的精神障碍。结果与Latimer（1983）关于肠易激综合征患者属于“神经症患者”亚类的观点一致。
Using a reliable and valid structured diagnostic interview scale (ADIS-R), and patients with careful medical characterization, we found significantly more diagnosable psychopathology, particularly anxiety disorders, among treatment seeking patients with irritable bowel syndrome than among comparable age and sex samples of treatment seeking patients with Inflammatory Bowel Disease. Significant differences were also found on the Hamilton Anxiety Rating Scale and Hamilton Rating Scale for Depression between IBS patients and the IBD patients and controls, who did not differ. Comparable levels of psychiatric disorder among parents of probands were found in all three groups. The results are consistent with Latimer''s (1983) notion of IBS patients being a subclass of ''neurotics''.