Sound stimulation increases the cerebral glucose:oxygen quotient in the fetal sheep.
Sound stimulation increases the cerebral glucose:oxygen quotient in the fetal sheep.
复制标题
声音刺激会增加胎羊的脑葡萄糖：氧商。
DOI：
10.1113/expphysiol.1993.sp003718
复制
发表时间：
1993
影响因子：
2.7
通讯作者：
Salha,SD
中科院分区：
文献类型：
--
作者：
Chao,CR;Glenford,PG;Karibo,EJ;Salha,SD
我们试图确定胎儿羊在声音刺激下的大脑葡萄糖代谢命运。在声音刺激期间，血氧含量显著降低6 - 7%。脑糖氧商由0.88 +/ - 0.08升高至1.13 +/ - 0.12（均数+/ - s.e.m., P < 0.01）。这与刺激糖酵解的现象是一致的，在其他模型中，糖酵解已被证明会增加脑乳酸浓度。
We sought to determine the cerebral metabolic fate of glucose during sound stimulation in near‐term fetal sheep. Blood oxygen content was significantly decreased by 6‐7% during sound stimulation. The cerebral glucose:oxygen quotient increased from 0.88 +/− 0.08 to 1.13 +/− 0.12 (mean +/− S.E.M., P < 0.01). This is consistent with the phenomenon of stimulated glycolysis which has been shown to increase brain lactate concentration in other models.