BIOLOGICAL AGE AND ITS ESTIMATION .3. INTRODUCTION OF A CORRECTION TO THE MULTIPLE-REGRESSION MODEL OF BIOLOGICAL AGE AND ASSESSMENT OF BIOLOGICAL AGE IN CROSS-SECTIONAL AND LONGITUDINAL-STUDIES

BIOLOGICAL AGE AND ITS ESTIMATION .3. INTRODUCTION OF A CORRECTION TO THE MULTIPLE-REGRESSION MODEL OF BIOLOGICAL AGE AND ASSESSMENT OF BIOLOGICAL AGE IN CROSS-SECTIONAL AND LONGITUDINAL-STUDIES
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DOI:
10.1016/0531-5565(84)90016-0
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发表时间:
1984-01-01
影响因子:
3.9
通讯作者:
ZHUK, EV
ZHUK, EV
中科院分区:
医学2区
文献类型:
--
作者:
DUBINA, TL;MINTS, AY;ZHUK, EV

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为消除生物学年龄估计中的系统误差,提出了生物学年龄多元回归模型的修正方法。个体的实足年龄与样本中年之间的差异越大,校正值越大。通过测量握力、短时记忆和振动触觉敏感度3项生理指标,对60-100岁表面健康人群的BA估计值进行了评估。引入的校正允许比较BA估计的同一个人从重复观察。初步结果表明,随着年龄的增长,脑动脉的变化至少有4种类型。
To eliminate systematic error inherent in assessment of an individual biological age (BA), a correction is suggested for the multiple regression model of BA. The larger the difference between an individual''s chronological age and middle age of the sample, the greater the correction value. BA estimates of apparently healthy people of 60-100 yr were assessed using measurements of 3 physiological indices: hand grip strength, short-time memory and vibrotactile sensitivity. Introduction of the correction allowed comparison of BA estimates of the same individual obtained from repeated observations. Preliminary results show there are at least 4 types of the BA changes with advancing age.