Epidemic resurgence of Chikungunya virus in democratic Republic of the Congo: Identification of a new central African strain

Epidemic resurgence of Chikungunya virus in democratic Republic of the Congo: Identification of a new central African strain
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DOI:
10.1002/jmv.20168
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发表时间:
2004-10-01
影响因子:
12.7
通讯作者:
Peyrefitte, CN
Peyrefitte, CN
中科院分区:
医学3区
文献类型:
--
作者:
Pastorino, B;Muyembe-Tamfum, JJ;Peyrefitte, CN

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基孔肯雅病毒在刚果民主共和国金沙萨的一次城市流行病中死灰复燃,此前39年没有对该病毒进行任何分离。从9例有临床症状的患者血清中分离出基孔肯雅病毒。每个分离株的E1/3'UTR基因组区域的部分序列为1200 bp。所有序列都聚集在中非谱系中。它们构成刚果民主共和国基孔肯雅病毒参考序列。
The resurgence of Chikungunya virus is described during an urban epidemic in Kinshasa Democratic Republic of the Congo, after 39 years without any isolation of the virus. Chikungunya virus was isolated in sera from nine patients with clinical symptoms. A 1,200 bp long partial sequence of the E1/3'UTR genomic region was determined for each isolate. All sequences clustered in the central African lineage. They constitute Chikungunya virus reference sequences for the Democratic Republic of the Congo.