A chemically-driven molecular information ratchet
A chemically-driven molecular information ratchet
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DOI：
10.1021/ja7102394
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发表时间：
2008-02-13
影响因子：
15
通讯作者：
Slawin, Alexandra M. Z.
中科院分区：
文献类型：
--
作者：
Alvarez-Perez, Monica;Goldup, Stephen M.;Slawin, Alexandra M. Z.
描述了一种化学驱动的分子信息棘轮。在手性催化剂的影响下，通过苯甲酰化将[2]轮烷中的平衡大环分布从其50：50的线结合位点群体驱动到33：67的比例。该反应对应于通过穿梭相互转化的轮烷共构象的动态动力学拆分。
A chemically driven molecular information ratchet is described. The equilibrium macrocycle distribution in a [2]rotaxane is driven away from its 50:50 population of thread binding sites to a 33:67 ratio by benzoylation under the influence of a chiral catalyst The reaction corresponds to a dynamic kinetic resolution of rotaxane co-conformers that interconvert through shuttling.