Therapeutic pars plana vitrectomy for chronic uveitis: a retrospective study of the long-term results

Therapeutic pars plana vitrectomy for chronic uveitis: a retrospective study of the long-term results
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治疗性玻璃体切除术治疗慢性葡萄膜炎:长期结果的回顾性研究

DOI:
10.1007/bf00220702
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发表时间:
1996
期刊:
Graefe's Archive for Clinical and Experimental Ophthalmology
影响因子:
--
通讯作者:
H. Verbraeken
H. Verbraeken
中科院分区:
--
文献类型:
--
作者:
H. Verbraeken

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摘要:背景:玻璃体切除对慢性葡萄膜炎具有诊断和治疗双重价值。本文探讨玻璃体切除术的治疗价值。方法:回顾性研究25只眼的玻璃体切割手术。对于有严重玻璃体混浊或黄斑褶皱的患者,以及对葡萄膜炎的常规治疗反应不佳或根本没有反应的患者,可以考虑手术治疗。平均随访时间为4.5年,随访时间从2年到12年不等。•结果:56%(14/25)的眼睛视力得到改善。24%的眼睛(6/ 25)视力稳定。40%(10/25)的黄斑水肿消失,60%(15/25)的黄斑水肿持续。9只持续黄斑水肿的眼睛中有2只发展为黄斑孔。6只眼睛中有4只眼睛复发,1只眼睛复发,只有1只眼睛治愈。12%的眼睛(3/25)随后经历了葡萄膜炎复发,需要进行全身治疗。1例患者在玻璃体切除术后出现牵引性视网膜脱离伴玻璃体视网膜病变。44%(11/25)眼无并发症或复发。结论:玻璃体切除术在慢性葡萄膜炎的治疗中具有明确的地位,无论是在功能水平上,改善或稳定视力,还是在治疗水平上,可能减少或停止全身治疗。
Abstract• Background: Pars plana vitrectomy has both diagnostic and therapeutic potential in chronic uveitis. In this paper the therapeutic value of vitrectomy is investigated. • Methods: This is a retrospective study on 25 eyes that underwent pars plana vitrectomy with therapeutic intent. Surgery was considered in patients with severe vitreous clouding or macular pucker and in those who responded poorly or not at all to conventional treatment for uveitis. The mean period of follow up was 4.5 years, varying from 2 to 12 years.• Results: Improved vision was observed in 56% of the eyes (14/25). Twenty-four percent of the eyes (6/ 25) had stable vision. Macular edema disappeared in 40% (10/25) of cases and persisted in 60% (15/25). Two of the nine eyes with persistent macular oedema progressed to a macular hole. Four of the six eyes with macular pucker suffered recurrence, one ended in phythisis, while the pucker was cured in only one patient. Twelve percent of the eyes (3/25) subsequently experienced a recrudescence of uveitis, making systemic treatment necessary. One patient presented, after vitrectomy, a traction retinal detachment with proliferating vitreoretinopathy. No complications or recurrences were seen in 44% of the eyes (11/25).• Conclusion: Vitrectomy has a definite place in the treatment of chronic uveitis, both on the functional level, with improvement or stabilisation of visual acuity and on the therapeutic level, with possible reduction or cessation of systemic treatment.
中间葡萄膜炎的手术治疗。
DOI: 10.1159/000429650
发表时间: 1992
期刊: Developments in ophthalmology
影响因子: --
作者:
Kaplan,HJ
通讯作者: Kaplan,HJ