Filling the data gaps on sickle cell anaemia in sub-Saharan Africa.
Filling the data gaps on sickle cell anaemia in sub-Saharan Africa.
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DOI：
10.1016/s2352-3026(22)00042-4
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发表时间：
2022-03
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通讯作者：
Williams TN
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作者：
Williams TN
尽管撒哈拉以南非洲是全球镰状细胞性贫血的中心，但直到最近，该疾病在该区域内一直被广泛忽视。1990年代后期，撒哈拉以南非洲5岁以下儿童的死亡率接近每1000例活产200例1，因此，每1000名儿童中有10人患有镰状细胞贫血等不治之症，这不是一个优先事项。然而，由于许多撒哈拉以南非洲国家正在经历流行病学和人口转型时期，总体儿童死亡率正在迅速下降，为出生时患有镰状细胞性贫血的儿童提供更好的护理现已成为一种必要。在倡导任何疾病时，早期优先考虑的是高质量数据。然而，关于撒哈拉以南非洲镰状细胞性贫血的可靠数据很少。新生儿筛查、国家登记和计算机化医院记录系统的缺失意味着，即使是大多数新生儿，也几乎没有可靠的数据可用
Although sub-Saharan Africa is the epicentre of sickle cell anaemia globally, until recently, the disease has been widely neglected within the region. During the late 1990s, mortality in children younger than 5 years in sub-Saharan Africa was close to 200 per 1000 livebirths, 1 and consequently, an incurable disease such as sickle cell anaemia affecting ten per 1000 children was not a priority. However, with many sub-Saharan African countries going through a period of epidemiological and demographic transition, overall child mortality is declining rapidly and provision of better care for children born with sickle cell anaemia has now become a necessity. 2, 3An early priority when advocating for any disease are high quality data. However, reliable data on sickle cell anaemia in sub-Saharan Africa are scarce. The absence of newborn screening, national registries, and computerised hospital record systems mean that few reliable data are available regarding even the most