Reduced quality of clot formation with gelatin-based plasma substitutes

Reduced quality of clot formation with gelatin-based plasma substitutes
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DOI:
10.1093/bja/80.2.204
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发表时间:
1998-02-01
影响因子:
9.8
通讯作者:
Ibbotson, RM
Ibbotson, RM
中科院分区:
医学1区
文献类型:
--
作者:
Mardel, SN;Saunders, FM;Ibbotson, RM

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我们已经研究了,在广泛的稀释使用技术的凝块重量,血栓弹力图和扫描电子显微镜,在体外形成的血凝块的物理特性时,新鲜血液稀释明胶为基础的胶体溶液与晶体对照。测试的胶体溶液(3.5%聚明胶肽(海脉素)和4%琥珀酰明胶(Gelofusine))产生的凝块具有降低的中位重量(P
We have studied, over a wide range of dilutions using techniques of clot weight, thrombelastography and scanning electron microscopy, the physical properties of a blood clot formed in vitro when fresh blood was diluted with gelatin-based colloid solutions compared with crystalloid controls. The colloid solutions tested (3.5% polygeline (Haemaccel) and 4% succinylated gelatin (Gelofusine)) produced clots that had reduced median weight (P