The Role of the Transcription Factor EGR1 in Cancer.
The Role of the Transcription Factor EGR1 in Cancer.
复制标题
转录因子 EGR1 在癌症中的作用。
DOI：
10.3389/fonc.2021.642547
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发表时间：
2021
影响因子：
4.7
通讯作者：
Zhao G
中科院分区：
文献类型：
--
作者：
Wang B;Guo H;Yu H;Chen Y;Xu H;Zhao G
Early growth response factor 1 (EGR1) is a transcription factor that is mainly involved in the processes of tissue injury, immune responses, and fibrosis. Recent studies have shown that EGR1 is closely related to the initiation and progression of cancer and may participate in tumor cell proliferation, invasion, and metastasis and in tumor angiogenesis. Nonetheless, the specific mechanism whereby EGR1 modulates these processes remains to be elucidated. This review article summarizes possible mechanisms of action of EGR1 in tumorigenesis and tumor progression and may serve as a reference for clinical efficacy predictions and for the discovery of new therapeutic targets.
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鉴定早期生长反应蛋白 1 (EGR-1) 作为 JUN 诱导多发性骨髓瘤细胞凋亡的新靶标
影响因子：
20.3
作者：
Chen, Lijuan;Wang, Siqing;Zhan, Fenghuang
通讯作者：
Zhan, Fenghuang
影响因子：
13.5
作者：
Chen, Hsin-An;Kuo, Tsang-Chih;Su, Jen-Liang
通讯作者：
Su, Jen-Liang
影响因子：
82.9
作者：
Fahmy, RG;Dass, CR;Khachigian, LM
通讯作者：
Khachigian, LM
DOI：
10.2217/fon.09.67
发表时间：
2009-09
期刊：
Future oncology (London, England)
影响因子：
--
作者：
Gitenay D;Baron VT
通讯作者：
Baron VT
影响因子：
2.9
作者：
Chen, Jie;Zhan, Ying;Gao, Qun
通讯作者：
Gao, Qun