Recovery of oculo-motor bias neglect patients after prism adaption
Recovery of oculo-motor bias neglect patients after prism adaption
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DOI：
10.1016/j.neuropsychologia.2004.01.007
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发表时间：
2004-01-01
期刊：
影响因子：
2.6
通讯作者：
Làdavas, E
中科院分区：
文献类型：
--
作者：
Angeli, V;Benassi, MG;Làdavas, E
患有“忽视阅读障碍”的患者通常会在阅读单词和非单词的左侧部分时出现错误。研究表明，“被忽视的阅读障碍”可以在短时间内适应楔形棱镜后得到改善[Neuropsychologia 40(2002) 718]，然而，这种改善的机制仍然未知。本研究通过考察棱镜适应（PA）对忽视阅读障碍患者的眼扫描行为的影响：(a)在阅读字母串时的第一次扫视着落位置；(b)注视时间的分布随单词和非单词的眼运动探索侧的变化而变化。这是为了评估适应后可能发生的变化（阅读表现）是否归因于眼动系统的重置。记录右脑损伤左半脑忽视伴“忽视性阅读障碍”患者单次棱柱形暴露前后的眼球运动表现。然后将实验忽视患者在PA前后的结果与佩戴中性镜片护目镜的对照组忽视患者的结果进行比较。此外，为了提供字母串阅读时眼扫描行为的规范数据，我们还对神经健康的受试者进行了研究。经过一次棱镜适应训练后，结果显示，实验忽视患者的忽视阅读障碍有所改善，左侧字母串的探索增加，第一次左侧扫视的幅度增加。相比之下，在控制忽视患者中，忽视阅读障碍以及眼运动系统行为在使用中性镜片护目镜后保持不变。这些发现表明，单棱柱体适应诱导的有益效应可能被认为是感觉刺激和眼-运动系统重置之间的复杂相互作用。(C) 2004 Elsevier Ltd.版权所有。
Patients with "neglect dyslexia" usually make errors in reading the left part of words and non-words. It has been shown that "neglect dyslexia" can improve following a short period of adaptation to wedge prisms [Neuropsychologia 40 (2002) 718], however the mechanisms underlying this amelioration are still unknown. The present study evaluated the effect of prism adaptation (PA) on ocular scanning behaviour of neglect dyslexia patients by investigating: (a) the first saccade landing position during reading a letter string and (b) the distribution of fixation time as a function of the side of oculo-motor exploration of words and non-words. This in order to assess whether possible changes (in reading performance) after the adaptation might be attributed to a resetting of the oculo-motor system. Eye movements' performances were recorded before and after a single prismatic exposure on right brain-damaged patients with left hemispatial neglect and "neglect dyslexia". The results obtained in Experimental neglect patients before and after PA were then compared to that of control neglect patients, who were wearing goggles with neutral lenses. Moreover, in order to provide normative data on ocular scanning behaviour during letter string reading, neurologically healthy subjects were also studied.Following a single session of prism adaptation, the results showed, in the Experimental neglect patients, an improvement of neglect dyslexia, an increased left-sided exploration of the letter string and an increased amplitude of the first left-sided saccade. In contrast, in the Control neglect patients, neglect dyslexia as well as the oculo-motor system behaviour, remained the same after the use of goggles with neutral lenses. These findings demonstrate that the beneficial effect induced by a single prismatic adaptation may be conceived as a complex interaction between sensory stimulation and a resetting of oculo-motor system. (C) 2004 Elsevier Ltd. All rights reserved.