Evaluation of effective connectivity of motor areas during motor imagery and execution using conditional Granger causality
Evaluation of effective connectivity of motor areas during motor imagery and execution using conditional Granger causality
复制标题
使用条件格兰杰因果关系评估运动想象和执行过程中运动区域的有效连接
DOI：
10.1016/j.neuroimage.2010.08.071
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发表时间：
2011-01-15
期刊：
影响因子：
5.7
通讯作者：
Chen, Huafu
中科院分区：
文献类型：
--
作者：
Gao, Qing;Duan, Xujun;Chen, Huafu
基于功能磁共振成像(FMRI)数据，采用条件格兰杰因果关系和图论方法，探讨了运动执行(ME)和运动想象(MI)重叠核心区之间的有效连接网络。我们的结果显示，在右手操作时，所选择的种子区域之间的有效连接回路比在左手操作时更多，这意味着右手操作的大脑不对称对有效连接网络的影响。ME期间的因果联系比MI期间更多，这表明ME网络可能比MI网络有一些额外的连接来执行公开的物理运动。此外，信息流的输入-输出程度提示左侧背侧运动前皮质(PMD)、顶下小叶(IPL)和顶上小叶(SPL)是ME/MI任务的因果来源，突出了左侧PMD、IPL和SPL的主导作用。这些发现描述了额顶环路运动相关核心区的因果联系，并可能表明ME和MI之间的因果网络的转换。(C)2010 Elsevier Inc.保留所有权利。
The effective connectivity networks among overlapped core regions recruited by motor execution (ME) and motor imagery (MI) were explored by means of conditional Granger causality and graph-theoretic method, based on functional magnetic resonance imaging (fMRI) data. Our results demonstrated more circuits of effective connectivity among the selected seed regions during right-hand performance than during left-hand performance, implying the influences of brain asymmetry of right-handedness on effective connectivity networks. The increased causal connections were found during ME than during MI, suggesting that the ME network may have some additional connections compared to MI networks to execute the overt physical movement. Furthermore, the In-Out degrees of information flow suggested left dorsal premotor cortex (PMd), inferior parietal lobule (IPL) and superior parietal lobule (SPL) as causal sources in ME/MI tasks, highlighting the dominant function of left PMd, IPL and SPL These findings depicted the causal connectivity of motor related core regions in fronto-parietal circuit and might indicate the conversion of causal networks between ME and MI. (C) 2010 Elsevier Inc. All rights reserved.