[Stress and periodontitis].
[Stress and periodontitis].
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DOI：
10.5177/ntvt.2020.06.20032
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发表时间：
2020-06-01
期刊：
影响因子：
--
通讯作者：
Loos, B G
中科院分区：
文献类型：
--
作者：
Pitzurra, L;Loos, B G
牙周炎和牙周炎可能会恶化，免疫力下降。各种原因会降低宿主的免疫适合性，从而破坏宿主和微生物群之间的平衡。其中，生活方式因素，如压力和吸烟，可能会对免疫健康产生负面影响。压力和牙周炎以及急性坏死性溃疡性牙周炎或牙周炎之间的关系已被证明。有迹象表明，神经元能够分泌促炎细胞因子和趋化因子，这些细胞因子和趋化因子会加剧牙周组织的慢性炎症反应，损害免疫健康。体外研究表明，较高的皮质醇水平可能有助于牙龈假单胞菌的生长。应激作为牙周炎的危险因素以及应激对牙周治疗结果的负面影响很难在临床上估计。然而，关注和意识到压力是牙周炎风险因素的一个方面，可以减少它对免疫健康的负面影响。
Gingivitis and periodontitis can worsen with reduced immune fitness. Various causes can reduce immune fitness in a host, as a result of which the balance between the host and the microbiome is disturbed. Among others, lifestyle factors, such as stress and smoking, can have a negative influence on immune fitness. An association has been demonstrated between stress and periodontitis and also acute necrotising ulcerative gingivitis or periodontitis. There are indications that neurons are able to secrete pro-inflammatory cytokines and chemokines that worsen chronic inflammatory reactions in the periodontium and compromise immune fitness. In vitro studies show high cortisol levels may contribute to the increased growth of P. gingivalis. Stress as a risk factor for periodontitis and the role of stress as a negative influence on the results of periodontal treatment are difficult to estimate clinically. Nevertheless, attention to and awareness of stress as an aspect of the comprehensive set of risk factors for periodontitis can diminish its negative impact on immune fitness.