Total Antioxidant Capacity and Superoxide Dismutase Activity Levels in Serum and Gingival Crevicular Fluid in Pregnant Women With Chronic Periodontitis
Total Antioxidant Capacity and Superoxide Dismutase Activity Levels in Serum and Gingival Crevicular Fluid in Pregnant Women With Chronic Periodontitis
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DOI：
10.1902/jop.2009.080218
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发表时间：
2009-03-01
影响因子：
4.3
通讯作者：
Karabulut, Erdem
中科院分区：
文献类型：
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作者：
Akahn, Ferda Alev;Baltacioglu, Esra;Karabulut, Erdem
背景资料：有证据表明，减少抗氧化剂（AO）防御牙周炎和妊娠和牙周炎和pregnancy.Methods之间的不良相互作用：在这项研究中，血清和龈沟液（GCF）的总AO能力（TAOC）和超氧化物歧化酶（SOD）酶浓度在妊娠慢性牙周炎（CP）患者与非妊娠患者进行了比较。进行牙周检查和GCF/血清样本，从33例妊娠CP患者（PCP），18例妊娠牙龈炎患者（PG）和21例牙周健康的妊娠对照（P-对照），监测在第一和第三孕期; 27名非妊娠妇女CP;和25名非妊娠对照妇女。结果：妊娠组与非妊娠组及CP组的月经周期参数均高于对照组，而TAOC和SOD浓度低于对照组（P
Background: There is evidence of reduced antioxidant (AO) defense in periodontitis and pregnancy and adverse interactions between periodontitis and pregnancy.Methods: In this study, serum and gingival crevicular fluid (GCF) total AO capacity (TAOC) and superoxide dismutase (SOD) enzyme concentrations in pregnant patients with chronic periodontitis (CP) were compared to those in non-pregnant patients. Periodontal examinations were performed and GCF/serum samples were obtained from 33 pregnant patients with CP (PCP), 18 pregnant patients with gingivitis (PG), and 21 periodontally healthy pregnant controls (P-controls), monitored in the first and third trimesters; 27 non-pregnant women with CP; and 25 non-pregnant control women. The concentrations of TAOC (automated measurement method) and SOD (spectrophotometric method) were determined.Results: Periodontal parameters were higher in pregnant patients versus non-pregnant patients and in the CP group compared to controls, whereas TAOC and SOD concentrations were lower (P