SERUM-ALBUMIN LEVEL AND PHYSICAL-DISABILITY AS PREDICTORS OF MORTALITY IN OLDER PERSONS
SERUM-ALBUMIN LEVEL AND PHYSICAL-DISABILITY AS PREDICTORS OF MORTALITY IN OLDER PERSONS
复制标题
DOI：
10.1001/jama.272.13.1036
复制
发表时间：
1994-10-05
影响因子：
120.7
通讯作者：
SORKIN, JD
中科院分区：
文献类型：
--
作者：
CORTI, MC;GURALNIK, JM;SORKIN, JD
目标。研究老年人群血清白蛋白水平与全因死亡率之间的关系，并评估白蛋白水平结合身体残疾状况在预测死亡率中的作用。队列研究，平均随访时间为3.7年。三个社区：马萨诸塞州东波士顿、康涅狄格州纽黑文、爱荷华州爱荷华州和爱荷华州华盛顿县。共有1486名男性和2630名女性，年龄在71岁及以上，他们同意抽血。在随访期间，447名男性和488名女性死亡。在两种性别中，随着白蛋白水平的降低，死亡率逐渐升高。在调整了年龄、种族、教育、慢性病和残疾状况后，低白蛋白血症（
Objectives.-To study the relationship between serum albumin level and all-cause mortality in an elderly population and to evaluate the role of albumin level in combination with physical disability status in predicting mortality.Design.-Cohort study with a mean follow-up of 3.7 years.Setting.-Three communities: East Boston, Mass, New Haven, Conn, and Iowa and Washington counties, Iowa.Subjects.-A total of 1486 men and 2630 women aged 71 years and older who consented to have blood drawn.Results.-During follow-up, 447 men and 488 women died. In both sexes, there was a graded increase in mortality rate with decreasing albumin level. After adjusting for age, race, education, chronic conditions, and disability status, hypoalbuminemia (