Structure and clinical correlates of obsessive-compulsive symptoms in a large sample of children and adolescents: a factor analytic study across five nations
Structure and clinical correlates of obsessive-compulsive symptoms in a large sample of children and adolescents: a factor analytic study across five nations
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DOI：
10.1007/s00787-016-0887-5
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发表时间：
2017-03-01
影响因子：
6.4
通讯作者：
Thomsen, P. H.
中科院分区：
文献类型：
--
作者：
Hojgaard, D. R. M. A.;Mortensen, E. L.;Thomsen, P. H.
儿童和青少年群体中强迫症 (OCD) 的基本结构仍有待确认。在本文中，我们报告了儿童耶鲁-布朗强迫量表（CY-BOCS）中各个强迫症项目的第一个因素分析研究。使用 CY-BOCS 症状检查表对从五个国家的诊所招募的 854 名强迫症患者（7-18 岁）样本进行了强迫症症状评估。对汇总数据进行探索性和验证性因子分析 (CFA)，以确定最佳因子结构。对不同模型的年龄和性别亚组进行了测试。此外，还测试了解在年龄和性别上的不变性，并探讨了与人口和临床因素的关联。三因素模型提供了最佳拟合解决方案。它由以下因素组成：（1）伤害/性，（2）对称/囤积，（3）污染/清洁。各亚组的因素结构对于年龄和性别而言是不变的。因素一与焦虑显着相关，因素二与抑郁和焦虑显着相关。因素三与抽动障碍和注意力缺陷/多动障碍（ADHD）呈负相关。女性在第二个因素上的得分高于男性。儿童和青少年的强迫症症状结构在不同年龄和性别之间是一致的，并且与近期儿童和青少年的结果相似，尽管囤积可能不是一个单独的因素。我们的三因素结构与早期成人研究中所见的结构几乎相同。常见的精神障碍与不同因素有特定的关联模式。
The underlying structure of obsessive-compulsive disorder (OCD) remains to be confirmed in child and adolescent populations. In this paper we report the first factor analytic study of individual OCD items from Children's Yale-Brown Obsessive Compulsive Scale (CY-BOCS). OCD symptoms were assessed using the CY-BOCS symptom checklist in a sample of 854 patients with OCD (7-18 years of age) recruited from clinics in five countries. Pooled data were subjected to exploratory and confirmatory factor analysis (CFA) to identify the optimal factor structure. Various models were tested for age and gender subgroups. Also, the invariance of the solution across age and gender was tested and associations with demographic and clinical factors were explored. A three-factor model provided the best-fit solution. It consisted of the following factors: (1) harm/sexual, (2) symmetry/hoarding, (3) contamination/cleaning. The factor structure was invariant for age and gender across subgroups. Factor one was significantly correlated with anxiety, and factor two with depression and anxiety. Factor three was negatively correlated with tic disorder and attention-deficit/hyperactivity disorder (ADHD). Females had higher scores on factor two than males. The OCD symptom structure in children and adolescents is consistent across age and gender and similar to results from recent child and adolescents although hoarding may not be a separate factor. Our three-factor structure is almost identical to that seen in early studies on adults. Common mental disorders had specific patterns of associations with the different factors.