Ring‐Closing Olefin Metathesis for the Synthesis of Benzene Derivatives.
Ring‐Closing Olefin Metathesis for the Synthesis of Benzene Derivatives.
复制标题
用于合成苯衍生物的闭环烯烃复分解反应。
DOI：
10.1002/chin.200708068
复制
发表时间：
2007
期刊：
影响因子：
--
通讯作者：
T. Imamoto
中科院分区：
文献类型：
--
作者：
Kazuhiro Yoshida;Fumihiro Kawagoe;N. Iwadate;Hidetoshi Takahashi;T. Imamoto
以1,4,7 -三烯- 3 -醇为原料，采用钌催化的串联闭环烯烃转化法(RCM)/脱水，以优异的收率合成了苯衍生物。将该方法扩展到串联RCM/氧化工艺中，以获得苯酚和苯胺衍生物。该方法与基于芳香取代的经典路线相比具有许多优点。
Benzene derivatives were synthesized in excellent yield from 1,4,7‐trien‐3‐ols by tandem ruthenium‐catalyzed ring‐closing olefin metathesis (RCM)/dehydration. The method was extended to the tandem RCM/oxidation process to obtain phenol and aniline derivatives. This method displays many advantages over aromatic‐substitution‐based classical routes.