Asymptomatic pharyngeal carriage of beta-haemolytic streptococci and streptococcal pharyngitis among patients at an urban hospital in Croatia
Asymptomatic pharyngeal carriage of beta-haemolytic streptococci and streptococcal pharyngitis among patients at an urban hospital in Croatia
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克罗地亚一家城市医院患者的无症状咽部携带β-溶血性链球菌和链球菌性咽炎
DOI：
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发表时间：
1993
影响因子：
13.6
通讯作者：
N. Kuzmanović
中科院分区：
文献类型：
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作者：
J. Begovac;E. Bobinac;B. Benić;B. Desnica;T. Maretić;A. Bašnec;N. Kuzmanović
在克罗地亚萨格勒布传染病大学医院进行的一项为期一年的研究中，对无症状喉咙携带β-溶血性链球菌的比率进行了调查。对 1796 名患者进行了喉咙运输调查，其中没有一人出现喉咙痛或呼吸道感染的体征和/或症状。 β-溶血性链球菌携带率为8.3%，其中A组链球菌为6%，B组为1.3%，C组为0.3%，F组为0.1%。 6 至 14 岁年龄组的发病率最高：所有链球菌组为 13.8%，单独 A 组为 11.7%。年龄较大的人群中非 A 型链球菌的比例较高。扁桃体切除的个体较少成为携带者。没有观察到性别或季节依赖性变化。在一项对 629 名咽炎患者进行的为期四个月的研究中，咽部培养结果显示：A 组链球菌占 44.7%，B 组占 1.7%，C 组占 0.8%，G 组占 0.6%。与咽炎患者的 A 组链球菌率相比，携带者的 A 组链球菌率表明，大约四分之一的咽炎培养阳性学童实际上并未真正感染，而只是目前患有非链球菌病因的喉咙痛的携带者。 对 605 名咽炎患者（96.2%）使用了抗生素； 571 例 (94.4%) 的病例在培养结果出来之前就发生了这种情况。在获得培养阴性结果后，只有 28.5% 的病例停止治疗。咽部培养是A群链球菌感染的实验室检测标准，对我院咽炎患者的治疗应该有更大的影响。
In a one-year study at the University Hospital of Infectious Diseases in Zagreb, Croatia the rate of asymptomatic throat carriage of beta-haemolytic streptococci was investigated. Throat carriage was investigated in 1796 patients, none of whom had a sore throat nor signs and/or symptoms of a respiratory tract infection. The carrier rate of beta-haemolytic streptococci was 8.3%, for group A streptococci 6%, group B 1.3%, group C 0.3% and group F 0.1%. The highest rate was observed in the 6 to 14 year age group: 13.8% for all streptococcal groups, 11.7% for group A alone. The proportion of non-A streptococci was higher in older age groups. Tonsillectomised individuals were less frequently carriers. No sex or season-dependent variations were observed. In a four-month study of 629 patients with pharyngitis the throat cultures yielded: group A streptococci in 44.7%, group B in 1.7%, group C in 0.8%, and group G in 0.6% of the patients. Group A streptococcal rates in carriers compared to rates in patients with pharyngitis suggest that approximately one fourth of the schoolchildren with culture-positive pharyngitis actually are not truly infected, but only carriers currently having a sore throat of non-streptococcal etiology.Antibiotics were administrated to 605 (96.2%) patients with pharyngitis; in 571 (94.4%) of the cases before culture results became available. After culture-negative results were obtained the therapy was discontinued in only 28.5% of the cases. The throat culture is the standard for laboratory testing of group A streptococcal infection and should have more influence on the management of patients with pharyngitis at our hospital.