The Dynamic Kaleidoscope of RNA Biology in Plants
The Dynamic Kaleidoscope of RNA Biology in Plants
复制标题
植物 RNA 生物学的动态万花筒
DOI：
10.1104/pp.19.01558
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发表时间：
2020-01-01
期刊：
影响因子：
7.4
通讯作者：
Seki, Motoaki
中科院分区：
文献类型：
--
作者：
Bailey-Serres, Julia;Zhai, Jixian;Seki, Motoaki
RNA生物学在植物中的万花筒在这8个更新评论，1封信和22篇研究文章的焦点问题中进行了探索。这些贡献是按RNA类型、合成位置和活性排序的。但情况并不简单：DNA和RNA之间的关系是万花筒，有镜子、反射和重复的模式，很容易因组成而改变和改变。rna具有动态结构，经历多种修饰，在发育和环境反应中发挥多种功能。在碱基修饰和加工之后，它们在不同或特定的位置起作用，涉及由rna结合蛋白和其他rna的彩色调色板控制的复杂过程。rna可以将信息传递到合成位点以外的细胞，甚至超越了生物体和王国的界限。当模式改变时，就像万花筒转动一样，rna可以通过异构体的产生、加工、共价修饰和衰变过程来改变形状。外转录组特异性腺苷转化为甲基-6-腺苷（m6A）和其他非dna编码的转录后修饰的识别刺激了研究人员探索这些RNA变异的原因和影响。这篇文章说明了活跃的活动，并阐明了RNA生物学在生物技术和农业中的应用的新机会。
The kaleidoscope of RNA biology within plants is explored in this Focus Issue of eight Update reviews, one letter, and 22 research articles. The contributions are sorted by RNA type, location of synthesis, and activity. But the picture is not simple: the relationship between DNA and RNA is kaleidoscopic, with mirrors, reflections, and repeated patterns, easily shifted and altered by composition. RNAs have dynamic structures, undergo a multitude of modifications, and serve diverse functions during development and environmental responses. They act, following base modification and processing, at varied or specific locations, involving complex processes controlled by a colorful palette of RNA-binding proteins and other RNAs. RNAs can deliver a message to cells beyond their site of synthesis, even transcending organismal and kingdom boundaries. As when patterns change as a kaleidoscope is turned, RNAs can be shape shifted through isoform production, processing, covalent modifications, and decay processes. The recognition of an epitranscriptome-specific adenosines converted to methyl-6-adenosine (m6A) and other posttranscriptional modifications not encoded by DNA-has stimulated researchers to probe the cause and effect of these RNA variations. This collection of articles illustrates vibrant activity and illuminates emerging opportunities for the application of RNA biology in biotechnology and agriculture.