Synthesis and Structure of Chiral (R)-2,2′-Bis-Silyl-Substituted 1,1′-Binaphthyl Derivatives
Synthesis and Structure of Chiral (R)-2,2′-Bis-Silyl-Substituted 1,1′-Binaphthyl Derivatives
复制标题
手性(R)-2,2′-双甲硅烷基取代的1,1′-联萘衍生物的合成与结构
DOI：
10.1246/cl.1999.1245
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发表时间：
1999
影响因子：
1.6
通讯作者：
HagiwaraHisahiro
中科院分区：
文献类型：
--
作者：
HoshiTakashi;ShionoiriHiroshi;SuzukiToshio;AndoMasayoshi;HagiwaraHisahiro
首次合成光学活性2,2'-双甲硅烷基取代的1,1'-联萘衍生物，(R)-(+)-2,2'-双(三甲基甲硅烷基)-1,1'-联萘((R)-(+)-1)和(R)-(−)-2,2'-双(二甲基苯基甲硅烷基)-1,1'-联萘((R)-(−)-2)，是通过手性 2,2'-二溴-1,1'-联萘 (DBBN) 的直接双甲硅烷基化来完成的。 (R)-(-)-2的分子结构和绝对构型已通过X射线晶体学测定。
First synthesis of optically active 2,2′-bis-silyl-substituted 1,1′-binaphthyl derivatives, (R)-(+)-2,2′-bis(trimethylsilyl)-1,1′-binaphthyl ((R)-(+)-1) and (R)-(−)-2,2′-bis(dimethylphenylsilyl)-1,1′-binaphthyl ((R)-(−)-2), has been accomplished by the direct bis-silylation of chiral 2,2′-dibromo-1,1′-binaphthyl (DBBN). The molecular structure and the absolute configuration of (R)-(−)-2 have been determined by means of X-ray crystallography.