Number of children and the risk of obesity in older women

Number of children and the risk of obesity in older women
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DOI:
10.1016/j.ypmed.2004.05.007
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发表时间:
2005-01-01
影响因子:
5.1
通讯作者:
Munger, RG
Munger, RG
中科院分区:
医学2区
文献类型:
--
作者:
Bastian, LA;West, NA;Munger, RG

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背景资料。这项研究的目的是调查老年妇女中与肥胖风险相关的活产数量、其他生殖因素和健康行为。数据是在犹他州以人群为基础的队列中通过面对面和电话采访收集的。本报告共包括2035名年龄在66岁至102岁之间的妇女。总体而言,403名(20%)老年女性被确定为肥胖。随着儿童数量的增加,肥胖率显著升高,呈现剂量-反应关系(P<0.05)。在调整了年龄、教育程度、婚姻状况、18岁时的BMI、口服避孕药的使用、子宫切除情况、体力活动、目前使用激素治疗的情况以及月经初潮年龄后,肥胖风险每增加一次活产就增加11%。在排除未分娩妇女的其他分析中,在调整了累计母乳喂养月份后,每生一次活着的婴儿肥胖的风险增加7%。在这群老年女性中,我们发现肥胖率更高,孩子的数量增加,这与社会经济地位和其他混杂因素无关。在一组老年女性中,肥胖率较高与孩子数量的增加有关,这与社会经济地位和其他混杂因素无关。(C)2004年癌症预防研究所和爱思唯尔公司。保留所有权利。
Background. The purpose of this study is to examine number of live births, other reproductive factors, and health behaviors in relation to obesity risk among older women.Methods. Data were collected during in-person and telephone-based interviews from a population-based cohort in Utah.Results. A total of 2,035 women aged 66-102 are included in this report. Overall, 403 (20%) older women were determined to be obese. The rates of obesity were significantly higher with increasing numbers of children, demonstrating a dose-response relationship (P < 0.05). After adjustment for age, education, marital status, BMI at age 18, use of oral contraceptives, hysterectomy status, physical activity, current use of hormone therapy, and age at menarche, the risk of obesity increased 11% with each additional live birth. In additional analyses that excluded nulliparous women, after adjusting for cumulative months of breast-feeding, the risk of obesity increased 7% with each live birth. In this cohort of older women, we found higher rates of obesity with increasing number of children that was independent of socioeconomic status and other confounding factors.Conclusions. In a cohort of older women, higher rates of obesity were associated with increasing number of children that was independent of socioeconomic status and other confounding factors. (C) 2004 The Institute For Cancer Prevention and Elsevier Inc. All rights reserved.