Doppler optical cardiogram gated 2D color flow imaging at 1000 fps and 4D in vivo visualization of embryonic heart at 45 fps on a swept source OCT system
Doppler optical cardiogram gated 2D color flow imaging at 1000 fps and 4D in vivo visualization of embryonic heart at 45 fps on a swept source OCT system
复制标题
DOI：
10.1364/oe.15.001627
复制
发表时间：
2007-02-19
期刊：
影响因子：
3.8
通讯作者：
Yang, Victor X. D.
中科院分区：
文献类型：
--
作者：
Mariampillai, Adrian;Standish, Beau A.;Yang, Victor X. D.
我们报道了一种多普勒光学心动图门控技术，用于增加多普勒光学相干断层扫描（DOCT）在胚胎心血管系统周期性运动成像时的有效帧率。这是通过Thorlabs扫描源DOCT系统完成的，该系统以每秒12帧（fps）的速度同时获取和显示结构和多普勒图像。门控技术允许以高达1000 fps的速度对非洲爪蟾胚胎（非洲爪蟾）心脏发育中的血流模式进行超高速可视化。此外，使用该门控技术，以45 fps的速度展示了四维（三维空间+时间）多普勒成像，产生了跳动心脏中复杂的心脏运动和血流动力学的详细可视化。(c) 2007年美国光学学会。
We report a Doppler optical cardiogram gating technique for increasing the effective frame rate of Doppler optical coherence tomography ( DOCT) when imaging periodic motion as found in the cardiovascular system of embryos. This was accomplished with a Thorlabs swept-source DOCT system that simultaneously acquired and displayed structural and Doppler images at 12 frames per second ( fps). The gating technique allowed for ultra-high speed visualization of the blood flow pattern in the developing hearts of African clawed frog embryos ( Xenopus laevis) at up to 1000 fps. In addition, four-dimensional ( three spatial dimensions + temporal) Doppler imaging at 45 fps was demonstrated using this gating technique, producing detailed visualization of the complex cardiac motion and hemodynamics in a beating heart. (c) 2007 Optical Society of America.