Importance of proper scaling of aerobic power when relating to cardiometabolic risk factors in children

Importance of proper scaling of aerobic power when relating to cardiometabolic risk factors in children
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DOI:
10.3109/03014460.2011.598561
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发表时间:
2011-09-01
影响因子:
1.7
通讯作者:
Bugge, Anna
Bugge, Anna
中科院分区:
医学4区
文献类型:
--
作者:
McMurray, Robert G.;Hosick, Peter A.;Bugge, Anna

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背景:心脏代谢危险因素(CMRF)和有氧功率(VO 2 max)之间的关系是有争议的,因为质量包括脂肪和无脂肪质量,而脂肪质量与CMRF独立相关。目的:检查用于测量VO 2 max的常用单位及其与平均血压(MBP)、总胆固醇(TC)、HDL胆固醇、甘油三酯(TG)的关系,胰岛素抵抗(HOMA-IR)和累积风险评分(z评分)。研究对象:1784名8-18岁青少年,其中女生938名,男生886名。VO 2 max通过踏车测力计以mL/min为单位进行估计,并按体重(kg)、去脂肪体重(kg(FFM))、体表面积(m2)、身高(cm)和异速生长(allometric)进行缩放。(mL/kg(0.67)/min)。CMRF和许多标度VO 2 max单位之间的未校正相关性显著(p < 0.0001),尤其是MBP、HOMA-IR、HDL和z评分,与TC和TG的相关性较低。校正血统后,性别,身高和体脂协会大大减弱(r < 0.09),除了MBP。结论:在人口的基础上,儿童的身体特征,特别是体脂,更相关的CMRF比任何缩放单位的VO 2 max;因此,需要照顾有关健身和健康问题。
sBackground: The relationship between cardiometabolic risk factors (CMRF) and aerobic power (VO2max) scaled as mL O-2 per kilogram body mass is controversial because mass includes both fat and fat-free mass, and fat mass is independently associated with the CMRF.Aim: To examine common units used to scale VO2max and their relationships to mean blood pressure (MBP), total cholesterol (TC), HDL cholesterol, triglycerides (TG), insulin resistance (HOMA-IR) and cumulative risk score (z-score). Subjects: 1784, 8-18 year-old youths, 938 girls and 886 boys.Methods: Fasting blood samples were obtained. VO2max was estimated in mL/min from cycle ergometry and scaled to body mass (kg), fat free mass (kg(FFM)), body surface area (m(2)), height (cm) and allometric (mL/kg(0.67)/min).Results: Unadjusted correlations between CMRF and many of the scaled VO2max units were significant (p < 0.0001), especially for MBP, HOMA-IR, HDL and z-score, with lower correlations for TC and TG. After adjusting for ancestry, sex, height and body fat associations were greatly weakened (r < 0.09), except for MBP.Conclusions: On a population basis, the physical characteristics of the child, especially body fat, are more related to CMRF than any scaled units of VO2max; thus care is needed when relating fitness and health issues.